Department of Experimental Psychology, Helmholtz Institute, Utrecht University, Heidelberglaan 1, 3584 CS, Utrecht, the Netherlands.
Department of Experimental Psychology, Helmholtz Institute, Utrecht University, Heidelberglaan 1, 3584 CS, Utrecht, the Netherlands.
Neuropsychologia. 2019 Sep;132:107138. doi: 10.1016/j.neuropsychologia.2019.107138. Epub 2019 Jul 10.
Optimal decision-making requires humans to predict the value and probability of prospective (rewarding) outcomes. The aim of the present study was to evaluate and dissociate the cortical mechanisms activated by information on an upcoming potentially rewarded target stimulus with varying probabilities. Electro-cortical activity was recorded during a cued Go/NoGo experiment, during which cue letters signaled upcoming target letters to which participants had to respond. The probability of target letter appearance after the cue letter and the amount of money that could be won for correct and fast responses were orthogonally manipulated across four task blocks. As expected, reward availability affected a prefrontally distributed reward-related positivity, and a centrally distributed P300-like event-related potential (ERP). Moreover, a late prefrontally distributed ERP was affected by probability information. These results show that information on value and probability, respectively, activates separate mechanisms in the cortex. These results contribute to a further understanding of the neural underpinnings of normal and abnormal reward processing.
最优决策要求人类预测未来（奖励）结果的价值和概率。本研究旨在评估和区分由具有不同概率的即将到来的潜在奖励目标刺激的信息激活的皮质机制。在提示 Go/NoGo 实验期间记录了电皮质活动，在此期间，提示字母提示参与者要响应的即将到来的目标字母。在提示字母之后目标字母出现的概率和正确快速响应可赢得的金额在四个任务块中正交操纵。正如预期的那样，奖励的可用性影响了额部分布的与奖励相关的正性，以及中央分布的类似 P300 的事件相关电位（ERP）。此外，晚期额分布的 ERP 受到概率信息的影响。这些结果表明，价值和概率信息分别激活了皮质中的不同机制。这些结果有助于进一步了解正常和异常奖励处理的神经基础。
