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原发性步态障碍筛查在帕金森病中的应用:与标准化测量方法的比较。

The Primary Gait Screen in Parkinson's disease: Comparison to standardized measures.

机构信息

Applied Neuromechanics Laboratory, Department of Applied Physiology and Kinesiology, University of Florida, 1864 Stadium Road, Gainesville, FL 32611, USA; Fixel Institute for Neurological Diseases, Movement Disorders and Neurorestoration Program, UF Health, University of Florida, 3450 Hull Road, Gainesville, FL 32607, USA.

Applied Neuromechanics Laboratory, Department of Applied Physiology and Kinesiology, University of Florida, 1864 Stadium Road, Gainesville, FL 32611, USA.

出版信息

Gait Posture. 2019 Sep;73:71-73. doi: 10.1016/j.gaitpost.2019.07.132. Epub 2019 Jul 5.

Abstract

BACKGROUND

Persons with Parkinson's disease exhibit gait deficits during comfortable-pace overground walking and data from pressure sensitive mats have been used to quantify gait performance. The Primary Gait Screen is a new assessment which includes gait initiation, overground walking, turning, and gait termination. Although overground assessments are useful, the Primary Gait Screen offers a more complex evaluation than traditional gait assessments.

RESEARCH QUESTION

Is the overground walking portion of the Primary Gait Screen comparable to traditional gait assessments?

METHODS

Persons with Parkinson's disease (N = 175; 47 F, 128 M; 67 ± 9 yrs) prospectively completed 4 passes at a self-selected speed and two trials of the Primary Gait Screen on an 8 m long pressure-sensing mat. Spatiotemporal gait variables were computed and a repeated-measures MANOVA with a Bonferroni correction compared the spatiotemporal variables from the Primary Gait Screen to the self-selected trials: gait velocity, cadence, step length, step time, and stride length.

RESULTS

The analyses failed to detect differences between the Primary Gait Screen and self-selected trials for gait velocity, step length, or stride length (p > .01). Post-hoc tests revealed decreased cadence and increased step time were the only differences between the Primary Gait Screen trials and the self-selected trial (p < .001).

SIGNIFICANCE

Differences seen in cadence and step time during the Primary Gait Screen may be attributed to patients' strategy, but are likely not clinically meaningful. The Primary Gait Screen appears to be a comparable assessment of overground walking in persons with Parkinson's disease, and may be a useful and accurate clinical assessment of walking.

摘要

背景

帕金森病患者在舒适速度的地面行走时表现出步态缺陷,并且已经使用压力敏感垫数据来量化步态表现。初步步态筛查是一种新的评估方法,包括步态启动、地面行走、转弯和步态终止。虽然地面评估很有用,但初步步态筛查提供了比传统步态评估更复杂的评估。

研究问题

初步步态筛查的地面行走部分是否与传统步态评估具有可比性?

方法

175 名帕金森病患者(47 名女性,128 名男性;67 ± 9 岁)前瞻性地以自我选择的速度完成了 4 次通过和在 8 米长的压力感应垫上进行了 2 次初步步态筛查试验。计算了时空步态变量,并使用重复测量的 MANOVA 与 Bonferroni 校正比较了初步步态筛查的时空变量与自我选择的试验:步行速度、步频、步长、步时和步长。

结果

分析未能检测到初步步态筛查与自我选择试验之间在步行速度、步长或步长方面的差异(p>0.01)。事后检验显示,步频降低和步时增加是初步步态筛查试验与自我选择试验之间仅有的差异(p<0.001)。

意义

在初步步态筛查期间看到的步频和步时差异可能归因于患者的策略,但不太可能具有临床意义。初步步态筛查似乎是帕金森病患者地面行走的一种可比较的评估方法,并且可能是一种有用且准确的临床步行评估方法。

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