Penchev Dimitar K, Ivanov Plamen G, Mutafchiyski Ventzislav M
Department of Endoscopic Endocrine Surgery and Coloproctology, Military Medical Academy, Sofia, Bulgaria.
Folia Med (Plovdiv). 2019 Jun 1;61(2):180-187. doi: 10.2478/folmed-2018-0069.
Rectal cancer located in distal third still remains a technical challenge for surgeons. Transanal total mesorectal excision with laparoscopic assistance is quite new surgical approach for rectal cancer treatment that seems to solve some of the associated technical issues. The aim of the study was to present our experience in laparoscopy-assisted transanal total mesorectal excision.
After obtaining approval from the local Ethics Committee, a single centre prospective double-arm comparative non-randomized trial was initiated. With recruiting still in progress at present, between 27.02.2017 and 01.10.2017 four laparoscopy-assisted transanal total mesorectal excision procedures and two laparoscopic total mesorectal excisions were performed in the department of Endoscopic Endocrine Surgery and Coloproctolgy at the Military Medical Academy in Sofia.
There is no conversion in both groups. No postoperative mortality 30 days after surgery. The quality of total mesorectal excision was satisfactory in all patients estimated by the Quirque classification. There was no distal or proximal tumor involvement of surgical margins. In one of the cases, we reported positive circumferential resection margin. We had two cases with postoperative morbidity.
Transanal total mesorectal excision with laparoscopic assistance is quite new minimally invasive surgical approach for rectal cancer treatment. Avoiding the procedure-related complications during the learning curve is essential before applying the method to every patient. Multicenter randomized control trial is needed so that we could answer the questions raised in this study.
位于直肠远端三分之一处的直肠癌对外科医生来说仍然是一项技术挑战。经肛门全直肠系膜切除术并辅以腹腔镜技术是一种全新的直肠癌治疗手术方法,似乎能解决一些相关的技术问题。本研究的目的是介绍我们在腹腔镜辅助经肛门全直肠系膜切除术中的经验。
在获得当地伦理委员会批准后,启动了一项单中心前瞻性双臂比较非随机试验。目前仍在招募患者,2017年2月27日至2017年10月1日期间,在索非亚军事医学院内镜内分泌外科和结直肠外科进行了4例腹腔镜辅助经肛门全直肠系膜切除术和2例腹腔镜全直肠系膜切除术。
两组均未出现中转开腹情况。术后30天内无死亡病例。根据Quirque分类法评估,所有患者的全直肠系膜切除质量均令人满意。手术切缘无远端或近端肿瘤累及。在其中1例病例中,我们报告了环周切缘阳性。我们有2例患者出现术后并发症。
腹腔镜辅助经肛门全直肠系膜切除术是一种全新的直肠癌微创治疗手术方法。在将该方法应用于每一位患者之前,在学习曲线阶段避免与手术相关的并发症至关重要。需要进行多中心随机对照试验,以便我们能够回答本研究中提出的问题。