Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska.
Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska; Department of Dermatology, Keck Medicine of the University of Southern California, Los Angeles, California.
J Am Acad Dermatol. 2019 Aug;81(2):581-599. doi: 10.1016/j.jaad.2019.03.087.
Definitions of skin cancer recurrence are variable and nonstandardized, which can lead to inconsistent and potentially inappropriate management of tumors of uncertain recurrence status. Defining recurrence is important given the potential association with metastasis in both melanoma and nonmelanoma skin cancer. A review of the literature across multiple disciplines involved in the care of skin cancer patients reveals that although criteria for recurrence are provided in the majority of cases, most are vague and inconsistent. Given the presumably increased morbidity and mortality associated with recurrent tumors, accurate identification and appropriate management is paramount. In addition, value-based health care necessitates validated and relevant outcome measures that are standardized and, thus, enable tracking of comparable and corresponding outcomes. A universal definition of localized skin cancer recurrence would ultimately allow for improved surveillance and informed therapeutic strategies to decrease morbidity and mortality of patients afflicted with skin cancer, the most common cancer nationwide.
皮肤癌复发的定义各不相同且不规范，这可能导致对不确定复发状态的肿瘤的管理不一致且潜在不当。鉴于黑色素瘤和非黑色素瘤皮肤癌都与转移有关，因此定义复发很重要。对涉及皮肤癌患者护理的多个学科的文献进行回顾，结果显示，尽管大多数情况下都提供了复发的标准，但大多数标准都模糊且不一致。鉴于与复发性肿瘤相关的发病率和死亡率增加，准确识别和适当管理至关重要。此外，基于价值的医疗保健需要经过验证和相关的、标准化的结果衡量标准，从而能够跟踪可比和相应的结果。局部皮肤癌复发的通用定义最终将允许改善监测并制定明智的治疗策略，以降低全国最常见癌症——皮肤癌患者的发病率和死亡率。
