Abdollahi Azadeh, Jalalian Ezzatollah
UT Health Dental School, San Antonio, Texas, USA; Department of Kinesiology and Health, and Nutrition, University of Texas, San Antonio, United States.
Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia, Phone: +989123238296, e-mail:
J Contemp Dent Pract. 2019 Apr 1;20(4):489-493.
The aim of this clinical investigation was to compare the efficacy of fluoride varnish and potassium nitrate on the reduction of hypersensitivity of prepared teeth both pre and post cementation.
In this randomized clinical trial, patients who needed at least three single crowns fixed partial prosthesis were included. Two desensitizing agents including fluoride varnish and potassium nitrate were used in this study and compared to the control group (sterile saline). In each patient, each prepared tooth was randomly assigned to one group. The desensitizing agent was applied on prepared teeth immediately after tooth preparation. The sensitivity of the teeth was measured by means of an air sensitivity test based on the visual analog scale at five different time points: baseline (2 hours after preparation), 7 days after preparation, before cementation, after cementation and one-week post cementation. Data were analyzed by Kruskal-Wallis and Friedman tests with a significant level of 0.05.
Overall 300 vital abutment teeth needed full crown coverage in 100 patients were included. Both desensitizers' agents decreased the sensitivity of vital abutment teeth compared to the control group at every time intervals except at baseline ( = 0.089). There was no significant difference between fluoride varnish and potassium nitrate in the reduction of pre-cementation sensitivity while one week after cementation, sensitivity was more relieved by potassium nitrate compared to fluoride varnish ( = 0.023).
The application of both desensitizers is effective in sensitivity reduction of vital abutment teeth. Potassium nitrate, however, is more eligible one week after cementation compared to fluoride varnish.
Both potassium nitrate and fluoride varnish are capable of desensitizing prepared tooth for the fixed partial denture.
本临床研究的目的是比较氟化漆和硝酸钾在粘结前和粘结后降低预备牙过敏反应的疗效。
在这项随机临床试验中,纳入了至少需要三个单冠固定局部义齿的患者。本研究使用了两种脱敏剂,即氟化漆和硝酸钾,并与对照组(无菌生理盐水)进行比较。在每位患者中,每颗预备牙被随机分配到一组。在牙体预备后立即将脱敏剂应用于预备牙上。基于视觉模拟量表,通过空气敏感试验在五个不同时间点测量牙齿的敏感性:基线(预备后2小时)、预备后7天、粘结前、粘结后和粘结后一周。数据采用Kruskal-Wallis和Friedman检验进行分析,显著性水平为0.05。
总共纳入了100例患者中需要全冠修复的300颗活基牙。与对照组相比,除基线外(P = 0.089),两种脱敏剂在每个时间间隔均降低了活基牙的敏感性。在降低粘结前敏感性方面,氟化漆和硝酸钾之间没有显著差异,而在粘结后一周,与氟化漆相比,硝酸钾使敏感性得到更明显缓解(P = 0.023)。
两种脱敏剂的应用均能有效降低活基牙的敏感性。然而,与氟化漆相比,硝酸钾在粘结后一周更适用。
硝酸钾和氟化漆均能够使用于固定局部义齿的预备牙脱敏。