Mollazadeh Sanaz, Sadeghzadeh Oskouei Behnaz, Kamalifard Mahin, Mirghafourvand Mojgan, Aminisani Nayyereh, Jafari Shobeiri Mehri
Students' Research Committee, Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.
Midwifery Department, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic Address:
Int J Fertil Steril. 2019 Oct;13(3):230-235. doi: 10.22074/ijfs.2019.5601. Epub 2019 Jul 14.
The prevalence of endometriosis in the general population is estimated at 7-10%. There are various risk factors for this disease, including early menarche age, prolonged menstruation or no history of pregnancy. It seems that sexual activity leading to orgasm during menstruation increases the retrograde menstruation, sending endometrial tissue to an abnormal sites and thus increasing the risk of endometriosis. The present study is aimed to determine the association between sexual activity during menstruation and endometriosis.
This case-control study, conducted in the year 2017, recruited 555 women who were visited at Alzahra Hospital in Tabriz, Northwest of Iran. The case group comprised 185 women of reproductive age with confirmed endometriosis. The control group comprised 370 women of reproductive age without endometriosis visiting the hospital for other issues. Data was collected using a researcher-made questionnaire based on previous studies. Bivariate analysis was performed by the chi-squared test and multivariate analysis was done using conditional logistic regression to control confounding variables.
The sexual activity of the two groups during menstruation was significantly different. The occurrence of endometriosis in women who stated they had vaginal intercourse or non-coital sexual activities, leading to orgasm during menstruation, was significantly higher compared to those who stated they did not.
According to our findings, there is an association between sexual activities leading to orgasm during menstruation and endometriosis.
普通人群中子宫内膜异位症的患病率估计为7%-10%。该疾病存在多种风险因素，包括初潮年龄早、经期延长或无妊娠史。似乎经期性行为达到性高潮会增加经血逆流，使子宫内膜组织转移至异常部位，从而增加患子宫内膜异位症的风险。本研究旨在确定经期性行为与子宫内膜异位症之间的关联。
这项病例对照研究于2017年进行，招募了555名在伊朗西北部大不里士的阿尔扎赫拉医院就诊的女性。病例组包括185名确诊为子宫内膜异位症的育龄女性。对照组包括370名因其他问题到医院就诊的无子宫内膜异位症的育龄女性。数据通过基于以往研究由研究人员制作的问卷收集。采用卡方检验进行双变量分析，并使用条件逻辑回归进行多变量分析以控制混杂变量。
两组在经期的性行为存在显著差异。与表示没有在经期进行阴道性交或非性交性活动并达到性高潮的女性相比，那些表示有此类行为的女性患子宫内膜异位症的发生率显著更高。
根据我们的研究结果，经期性行为达到性高潮与子宫内膜异位症之间存在关联。
