Fekadu Ginenus, Abdisa Eba, Fanta Korinan
Clinical Pharmacy Unit, Department of Pharmacy, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.
Department of Psychiatry, School of Nursing and Midwifery, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.
BMC Res Notes. 2019 Jul 16;12(1):421. doi: 10.1186/s13104-019-4455-1.
Incidence and clinical outcomes of medication prescribing errors are common and potentially more harmful in the pediatric population than in the adult population. Hence, this study was aimed to assess the prevalence and types of medication prescribing errors in the pediatric wards of Nekemte Referral Hospital (NRH).
Of 384 pediatric patients included in the study, 241 (63%) were males and 116 (30.21%) of them were aged between 1-3 years. About 241 (62.76%) of the patients were treated based on empirical diagnosis and only 10 (2.60%) pediatrics had co-morbid disease. The most category of medication prescribing error was dosing error 251 (48.6%) followed by incorrect drug selection 98 (19.0%). Being critically ill (AOR = 5.31, 95% CI = 1.80-12.31, p = 0.003), route of administration via IV (AOR = 3.98, 95% CI = 1.85-11.15, p = 0.011) and via IV + IM route (AOR = 2.22, 95% CI = 1.05-9.25, p = 0.045) as well as 4-6 medications per patient (AOR = 3.10, 95% CI = 3.43-12.42, p = 0.012) and > 6 medications per patient (AOR = 7.23, 95% CI = 3.91-21.45, p < 0.001) were independent predictors of medication prescribing errors. Antibiotics were the most common classes of drugs responsible for prescribing errors.
用药处方错误的发生率及临床后果很常见，且在儿科人群中可能比在成人人群中危害更大。因此，本研究旨在评估内克姆特转诊医院（NRH）儿科病房用药处方错误的发生率及类型。
纳入本研究的384例儿科患者中，241例（63%）为男性，其中116例（30.21%）年龄在1至3岁之间。约241例（62.76%）患者基于经验性诊断进行治疗，仅有10例（2.60%）儿科患者患有合并症。用药处方错误最常见的类型是剂量错误，共251例（48.6%），其次是药物选择错误，共98例（19.0%）。危重症（调整后比值比[AOR]=5.31，95%置信区间[CI]=1.80至12.31，p=0.003）、静脉注射给药途径（AOR=3.98，95%CI=1.85至11.15，p=0.011）和静脉注射+肌内注射给药途径（AOR=2.22，95%CI=1.05至9.25，p=0.045）以及每位患者使用4至6种药物（AOR=3.10，95%CI=3.43至12.42，p=0.012）和每位患者使用>6种药物（AOR=7.23，95%CI=3.91至21.45，p<0.001）是用药处方错误的独立预测因素。抗生素是导致处方错误最常见的药物类别。
