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Moderate embryonic delay of paternal mitochondrial elimination impairs mating and cognition and alters behaviors of adult animals.中度胚胎期父源线粒体清除延迟会损害动物的交配和认知能力，并改变成年动物的行为。
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Reply to Annis et al.: Is quasi-Mendelian mtDNA competition enough to drive transmission of paternal mtDNA?对安妮斯等人的回复：准孟德尔式线粒体DNA竞争足以推动父系线粒体DNA的传递吗？
Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):14799-14800. doi: 10.1073/pnas.1909445116. Epub 2019 Jul 16.

本文引用的文献

1
Extraordinary claims require extraordinary evidence in asserted mtDNA biparental inheritance.在声称的线粒体DNA双亲遗传中，非凡的主张需要非凡的证据。
Forensic Sci Int Genet. 2020 Jul;47:102274. doi: 10.1016/j.fsigen.2020.102274. Epub 2020 Mar 12.
2
No further evidence for paternal leakage of mitochondrial DNA in humans yet.目前尚未发现人类线粒体DNA存在父系渗漏的进一步证据。
Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1821-1822. doi: 10.1073/pnas.1820533116. Epub 2019 Jan 23.
3
Reply to Lutz-Bonengel et al.: Biparental mtDNA transmission is unlikely to be the result of nuclear mitochondrial DNA segments.对卢茨 - 博嫩格尔等人的回复：双亲线粒体DNA传递不太可能是核线粒体DNA片段造成的结果。
Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1823-1824. doi: 10.1073/pnas.1821357116. Epub 2019 Jan 23.
4
Paternal comeback in mitochondrial DNA inheritance.线粒体DNA遗传中的父系回归。
Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1475-1476. doi: 10.1073/pnas.1821192116. Epub 2019 Jan 11.
5
Biparental Inheritance of Mitochondrial DNA in Humans.人类线粒体 DNA 的双亲遗传。
Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13039-13044. doi: 10.1073/pnas.1810946115. Epub 2018 Nov 26.
6
Paternal inheritance of mitochondrial DNA.线粒体DNA的父系遗传
N Engl J Med. 2002 Aug 22;347(8):576-80. doi: 10.1056/NEJMoa020350.
7
Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes.由于细胞核内嵌入的线粒体DNA假基因的PCR扩增，阿尔茨海默病患者和正常人中出现明显的线粒体DNA异质性。
Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14894-9. doi: 10.1073/pnas.94.26.14894.
8
Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice.异质性小鼠中不同线粒体DNA基因型的组织特异性选择
Nat Genet. 1997 May;16(1):93-5. doi: 10.1038/ng0597-93.

Quasi-Mendelian paternal inheritance of mitochondrial DNA: A notorious artifact, or anticipated behavior?

作者信息

Annis Sofia, Fleischmann Zoe, Khrapko Mark, Franco Melissa, Wasko Kevin, Woods Dori, Kunz Wolfram S, Ellis Peter, Khrapko Konstantin

机构信息

Department of Biology, Northeastern University, Boston, MA 02115.

Department of Experimental Epileptology and Cognition Research, University of Bonn, 53127 Bonn, Germany.

出版信息

Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):14797-14798. doi: 10.1073/pnas.1821436116. Epub 2019 Jul 16.

DOI:10.1073/pnas.1821436116
PMID:31311874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6660754/
Abstract
摘要