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Immunotherapy in Gastrointestinal Cancer: Where Do We Stand?

作者信息

Tannapfel Andrea, Reinacher-Schick Anke

机构信息

Institute of Pathology, Ruhr-University Bochum, Bochum, Germany.

Department of Hematology, Oncology and Palliative Care, Ruhr-University Bochum, Bochum, Germany.

出版信息

Visc Med. 2019 Mar;35(1):1-2. doi: 10.1159/000497294. Epub 2019 Feb 8.

DOI:10.1159/000497294
PMID:31312643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6597926/
Abstract
摘要

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4
Immunologic Biomarkers and Biomarkers for Immunotherapies in Gastrointestinal Cancer.胃肠道癌免疫生物标志物及免疫疗法生物标志物
Visc Med. 2019 Mar;35(1):3-10. doi: 10.1159/000496565. Epub 2019 Feb 4.
5
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial.曲妥珠单抗联合化疗与单纯化疗治疗 HER2 阳性晚期胃或胃食管交界腺癌（ToGA）：一项开放标签、随机对照的 3 期临床试验。
Lancet. 2010 Aug 28;376(9742):687-97. doi: 10.1016/S0140-6736(10)61121-X. Epub 2010 Aug 19.
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Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer.西妥昔单抗与化疗联合作为转移性结直肠癌的初始治疗方案
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J Exp Med. 2000 Oct 2;192(7):1027-34. doi: 10.1084/jem.192.7.1027.
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Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.人类胃肠道间质瘤中c-kit的功能获得性突变。
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Enhancement of antitumor immunity by CTLA-4 blockade.通过阻断CTLA-4增强抗肿瘤免疫力。
Science. 1996 Mar 22;271(5256):1734-6. doi: 10.1126/science.271.5256.1734.