Department of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, China.
Department of Gastroenterology, Affiliated Hospital of Youjiang Medical University for Nationlities, Baise, China.
Int J Food Sci Nutr. 2020 Mar;71(2):164-175. doi: 10.1080/09637486.2019.1631264. Epub 2019 Jul 17.
This study evaluated the relationship between grain consumption and the risk of gastric cancer. A total of 19 studies met the inclusion criteria. For whole grain consumption, there was a 13% reduction in the risk of gastric cancer ( = .003), and a subgroup analysis showed that a large amount of whole grain consumption reduced the risk of gastric cancer by 44% ( < .001). For refined grain consumption, there was a 36% increase in the risk of gastric cancer ( < .001); a subgroup analysis showed that a large and a moderate amount of refined grain consumption increased the risk of gastric cancer by 63% ( < .001) and 28% ( < .001), respectively. A large intake of whole grains might be protective against gastric cancer, whereas the ingestion of refined cereals may be a risk factor for gastric cancer. Moreover, the risk of cancer increases with the increase of refined grain intake.
本研究评估了谷物摄入与胃癌风险之间的关系。共有 19 项研究符合纳入标准。对于全谷物的摄入,胃癌的风险降低了 13%( = .003),亚组分析显示大量摄入全谷物可使胃癌风险降低 44%( < .001)。对于精制谷物的摄入,胃癌的风险增加了 36%( < .001);亚组分析表明,大量和适量摄入精制谷物使胃癌的风险分别增加了 63%( < .001)和 28%( < .001)。大量摄入全谷物可能对胃癌具有保护作用,而摄入精制谷物可能是胃癌的一个危险因素。此外,随着精制谷物摄入量的增加,癌症风险也会增加。