Inflammatory Eye Disease Clinic, Asociación Para Evitar la Ceguera en México, Hospital Dr Luis Sánchez Bulnes , México City, México.
Uveitis Clinic, Oftalmosanitas, Clínica Universitaria Colombia , Bogotá, Colombia.
Ocul Immunol Inflamm. 2020 May 18;28(4):626-631. doi: 10.1080/09273948.2019.1609527. Epub 2019 Jul 17.
To describe the ultrabiomicroscopy (UBM) characteristics in patients with uveitic, convalescent, and recurrent Vogt-Koyanagi-Harada (VKH) disease.
In this prospective, non-interventional, and observational study, all UBM variables, namely pars plicata and pars plana thickness, ciliochoroidal detachment, angle chamber, anterior chamber depth, ID2, and presence of ciliary processes, were compared between acute uveitic, convalescent, and chronic-recurrent phases.
Ninety-one eyes were analyzed. Ciliochoroidal detachment (20%) and unclear ciliary processes (15%) are the most characteristic findings of the uveitic phase. At 1 and 3 months, ciliochoroidal detachment is no longer observed. In recurrent phase, pars plicata and pars plana thickness increases again and then decreases after the first month of treatment. Convalescent-phase does not show significant differences in UBM variables after a 6-month follow up.
UBM may have a role in evaluating response to treatment in uveitic and recurrent phases and in the early detection of recurrences.
描述葡萄膜炎、恢复期和复发性 Vogt-小柳原田（VKH）病患者的超声生物显微镜（UBM）特征。
在这项前瞻性、非干预性和观察性研究中，比较了急性期、恢复期和慢性复发性葡萄膜炎患者的 UBM 所有变量，包括睫状体平坦部和睫状体平坦部厚度、睫状体脉络膜脱离、房角、前房深度、ID2 和睫状突的存在。
共分析了 91 只眼。睫状体脉络膜脱离（20%）和睫状突模糊（15%）是葡萄膜炎期最具特征性的发现。1 个月和 3 个月时，睫状体脉络膜脱离不再观察到。在复发性阶段，睫状体平坦部和睫状体平坦部厚度在治疗后第一个月再次增加，然后减少。在 6 个月的随访中，恢复期 UBM 变量无明显差异。
UBM 可用于评估葡萄膜炎和复发性疾病的治疗反应，并在早期发现复发。
