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PTW 60019 微 diamond 探测器的蒙特卡罗研究。

A Monte Carlo study on the PTW 60019 microDiamond detector.

机构信息

German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.

Institute of Medical Physics and Radiation Protection (IMPS), University of Applied Sciences Giessen, 35390, Giessen, Germany.

出版信息

Med Phys. 2019 Nov;46(11):5159-5172. doi: 10.1002/mp.13721. Epub 2019 Sep 24.

Abstract

PURPOSE

Data on the output correction factor for small photon beam dosimetry of the microDiamond detector manufactured by the company PTW can be found in a variety of papers. Referring either to measurements or to Monte Carlo (MC) calculations, they show substantial disagreements particularly at very small fields. This work reports results of a further MC study aiming at a better understanding of how specific properties of the microDiamond detector are influencing its output correction factor and whether this can explain at least some of the disagreements.

METHODS

In this study the method of a fluence-based decomposition of the dose conversion factor was used which is considered as a useful tool to understand the response of a detector in nonreference conditions. This decomposition method yields the following three factors: (a) the stopping power ratio water to diamond, (b) a perturbation factor p taking into account all fluence changes in the transition from a small water voxel at the point of dose determination to the bare diamond detector, and (c) a perturbation factor p taking into account all additional fluence changes in the fully simulated diamond detector caused by the material and design details outside the sensitive volume.

RESULTS

Monte Carlo calculated output correction factors were obtained for Co-60, 6 MV and 10 MV photon beams showing that the maximum variation with field size remained in the order of 2% for quadratic field sizes larger than about 0.3 cm. For field sizes smaller than about 0.5 cm a clear under-response is obtained at all three radiation qualities in agreement with all known MC calculations, however, in contrast to some measured result. The shape of the output correction factor can be well explained by an opposite mode of action between under-response expressed by the perturbation factor p and over-response expressed by the perturbation factor p where the first one is mainly influenced by volume averaging, and the second one by a back scatter effect of electrons from the diamond substrate into the sensitive volume.

CONCLUSION

The response of microDiamond detector can be well described under various measuring conditions by the dose conversion factor and the dependency of its fluence-based subfactors on detector characteristics. Monte Carlo simulations offer an improvement in the understanding particularly of small-field effects by relating the output correction factor to spectral fluence changes in the sensitive volume of the detector. The most significant influence factors are the finite size of the active volume and the presence of the high-density diamond substrate causing a field size-dependent backscattering. These perturbations are opposite in their effects. The diamond in the sensitive volume itself and in particular its density has almost no influence. Scattering of results at very small field sizes can be explained by different gradients of dose profiles around the beam axis at identical full width half maximum (FWHM) field size parameters and by possible deviations of the radius of the sensitive volume from the nominal radius. The backscattering effect also has an influence on the determination of profiles and for very small field sizes on the response at different rotation angles.

摘要

目的

关于 PTW 公司制造的 microDiamond 探测器的小光子束剂量学输出校正因子的数据,可以在各种论文中找到。无论是参考测量值还是蒙特卡罗(MC)计算值,它们都显示出很大的差异,尤其是在非常小的射野下。本工作报告了进一步的 MC 研究结果,旨在更好地了解 microDiamond 探测器的特定特性如何影响其输出校正因子,以及这是否可以解释至少部分差异。

方法

在这项研究中,使用了基于注量分解的剂量转换因子的方法,该方法被认为是理解探测器在非参考条件下响应的有用工具。这种分解方法产生了以下三个因子:(a)水对钻石的阻止本领比,(b)考虑到从剂量测定点的小水像素到裸露的钻石探测器的过渡中所有注量变化的微扰因子 p,以及(c)考虑到敏感体积外的材料和设计细节引起的完全模拟钻石探测器中的所有附加注量变化的微扰因子 p。

结果

对于 Co-60、6 MV 和 10 MV 光子束,蒙特卡罗计算得到的输出校正因子表明,随着射野尺寸的增大,最大变化仍然在 2%左右,对于大于约 0.3 cm 的方形射野。对于小于约 0.5 cm 的射野,在所有三种辐射质量下都得到了明显的低响应,这与所有已知的 MC 计算结果一致,但与一些测量结果相反。输出校正因子的形状可以很好地用微扰因子 p 和 p 之间的相反作用来解释,其中前者主要受体积平均的影响,后者受来自钻石衬底的电子背散射效应的影响。

结论

通过剂量转换因子和探测器特性对其注量子因子的依赖性,可以很好地描述 microDiamond 探测器在各种测量条件下的响应。蒙特卡罗模拟通过将输出校正因子与探测器敏感体积中的光谱注量变化相关联,特别是在小射野效应的理解方面有所提高。最显著的影响因素是有效体积的有限尺寸和高密度钻石衬底的存在,这导致了射野依赖性的背散射。这些微扰在其效果上是相反的。敏感体积中的钻石本身,特别是其密度,几乎没有影响。在非常小的射野尺寸下的结果散射可以用相同的全宽度半最大值(FWHM)射野尺寸参数下的束轴周围剂量分布的不同梯度来解释,也可以用敏感体积的半径与标称半径的可能偏差来解释。背散射效应也会影响轮廓的确定,对于非常小的射野尺寸,也会影响不同旋转角度的响应。

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