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直肠切除术后坏死性盆腔感染。内镜下真空辅助闭合疗法的罕见适应证。病例报告。

Necrotizing pelvic infection after rectal resection. A rare indication of endoscopic vacuum-assisted closure therapy. A case report.

作者信息

Řezáč Tomáš, Stašek Martin, Zbořil Pavel, Vomáčková Katherine, Bébarová Linda, Hanuliak Jan, Neoral Čestmír

机构信息

Department of Surgery I, University Hospital Olomouc, Olomouc 77900, Czech Republic.

Department of Surgery I, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc 77900, Czech Republic.

出版信息

Int J Surg Case Rep. 2019;61:44-47. doi: 10.1016/j.ijscr.2019.06.054. Epub 2019 Jun 27.

Abstract

INTRODUCTION

Anastomotic leak after colorectal surgery is a major problem associated with higher morbidity and mortality. In most cases of contained leaks, treatment recommendations are clear and effective. However, in rare cases like necrotizing pelvic infection, there is no clear treatment of choice, despite the mortality rate almost 21%. We present successful management with endoscopic vacuum-assisted closure therapy.

THE PRESENTATION OF A CASE

A 68-year-old female patient with BMI 26, hypothyroidism and high blood pressure was indicated to low anterior rectal resection because of high-risk neoplasia of lateral spreading tumor type of the upper rectum. Four days after the primary operation, sepsis (SOFA 12) with diffuse peritonitis and unconfirmed leak according to CT led to surgical revision with loop ileostomy. On postoperative days 6-10, swelling, inflammation and subsequent necrosis of the right groin and femoral region communicating with the leak cavity developed. The endoscopy confirmed a leak of 30% of the anastomotic circumference with the indication of debridement and endoscopic vacuum-assisted closure therapy. EVAC sessions with 3-4 day intervals healed the leak cavity. Secondary healing of the skin defects required 4 months.

CONCLUSION

Necrotizing pelvic infection after a leak of the colorectal anastomosis is a very rare complication with high morbidity and mortality. Endoscopic vacuum-assisted closure therapy should be implemented in the multimodal therapeutic strategy in case of major leaks, affecting up to 270° of the anastomotic circumference.

摘要

引言

结直肠手术后吻合口漏是一个与较高发病率和死亡率相关的主要问题。在大多数局限性漏的病例中,治疗建议明确且有效。然而,在坏死性盆腔感染等罕见病例中,尽管死亡率近21%,但尚无明确的治疗选择。我们介绍了内镜下真空辅助闭合疗法的成功应用。

病例介绍

一名68岁女性患者,体重指数(BMI)为26,患有甲状腺功能减退和高血压,因上段直肠侧向扩散肿瘤型高危肿瘤而接受低位前直肠切除术。初次手术后四天,出现败血症(序贯器官衰竭评估(SOFA)评分12分),伴有弥漫性腹膜炎,根据CT检查未确诊有漏,遂进行手术修正并做了袢式回肠造口术。术后第6至10天,右腹股沟和股部出现肿胀、炎症,随后与漏腔相通处发生坏死。内镜检查证实吻合口周长30%有漏,表明需要清创并采用内镜下真空辅助闭合疗法。每隔3至4天进行一次内镜下真空辅助闭合(EVAC)治疗,使漏腔愈合。皮肤缺损的二期愈合需要4个月。

结论

结直肠吻合口漏后发生的坏死性盆腔感染是一种非常罕见的并发症,发病率和死亡率都很高。对于影响吻合口周长达270°的大漏,应在内镜下真空辅助闭合疗法应纳入多模式治疗策略中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/211b/6630029/306b74618e1c/gr1.jpg

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