Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Menglun, China.
Industrial Crop Research Institute, Yunnan Academy of Agricultural Sciences, Kunming, China.
Nat Prod Res. 2021 Apr;35(7):1147-1152. doi: 10.1080/14786419.2019.1643862. Epub 2019 Jul 17.
Chemical investigation of has led to the isolation of two undescribed compounds, namely 17(20)-dyscusin B () and 17(20)-dyscusin B (), as well as three known ones (-). Structural elucidation was accomplished by the analysis of NMR, MS and IR data. Compounds and were a pair of Δ geometric isomers of pregnane steroids and showed the significant nitric oxide (NO) inhibitory activities.
对 进行了化学研究,分离得到了两个未被描述的化合物,分别是 17(20)-dyscusin B () 和 17(20)-dyscusin B (),以及三个已知的化合物 (-)。通过分析 NMR、MS 和 IR 数据完成了结构阐明。化合物 和 是一对 Δ 立体异构体的甾体化合物,表现出显著的一氧化氮 (NO) 抑制活性。