Lee Jun Soo, Zhang Yidan Xue, Pollack Lisa M, Luo Feijun
Division for Heart Disease and Heart Disease Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
ASRT, Inc., Atlanta, Georgia.
AJPM Focus. 2024 Oct 6;4(1):100285. doi: 10.1016/j.focus.2024.100285. eCollection 2025 Feb.
Heart disease poses a significant health and economic burden in the U.S., with considerable variations in outcomes across different racial and ethnic groups. The COVID-19 pandemic has further highlighted the disparities in healthcare utilization and costs associated with heart disease.
The authors used the 2021 Merative MarketScan Medicaid claims database to estimate the medical costs and healthcare utilization associated with heart disease by racial and ethnic groups and COVID-19 diagnosis status. This study focused on individuals aged ≥18 years continuously enrolled in a noncapitated insurance plan in 2021. The outcome measures included total medical expenditures and healthcare utilization, including the numbers of emergency department visits and inpatient admissions and length of inpatient stay. The authors employed a generalized linear model with a family of gamma and log links for medical costs, and a negative binomial regression was used for healthcare utilization. Three-way interactions of heart disease, COVID-19 diagnosis, and race and ethnicity categories were implemented after adjusting for age, sex, and comorbidities. The authors reported average marginal effects with 95% CIs.
Among 1,008,166 Medicaid beneficiaries, 8% had heart disease in 2021. The cost associated with heart disease was $10,819 per beneficiary in 2021 (95% CI=10,292; 11,347; <0.001). The cost was $15,840 (95% CI=14,389; 17,291; <0.001) for non-Hispanic Black individuals; $9,945 (95% CI=9,172; 10,718; <0.001) for non-Hispanic White; and $8,511 (95% CI=7,490; 9,531; <0.001) for Hispanic individuals. Individuals with a COVID-19 diagnosis ($19,638) had $9,541 (95% CI=7,049; 12,032; <0.001) higher costs associated with heart disease than those without COVID-19 ($10,098) (<0.001). Individuals with heart disease had higher numbers of emergency department visits (0.937 per beneficiary, 95% CI=0.913; 0.960), inpatient admissions (0.463 per beneficiary, 95% CI=0.455; 0.471), and average length of stay (2.541 days per admission, 95% CI=2.405; 2.677) than those without heart disease.
The study's findings showed that costs and healthcare utilization associated with heart disease are substantial in all racial and ethnic groups and the highest among non-Hispanic Black individuals. Furthermore, individuals with a COVID-19 diagnosis had approximately 2 times higher costs associated with heart disease than individuals without a COVID-19 diagnosis.
心脏病给美国带来了巨大的健康和经济负担,不同种族和族裔群体的疾病结果存在显著差异。新冠疫情进一步凸显了与心脏病相关的医疗保健利用和成本方面的差距。
作者利用2021年Merative MarketScan医疗补助索赔数据库,按种族和族裔群体以及新冠诊断状况估算与心脏病相关的医疗成本和医疗保健利用情况。本研究聚焦于2021年连续参保非人头保险计划的18岁及以上个体。结果指标包括总医疗支出和医疗保健利用情况,如急诊就诊次数、住院人数及住院时长。作者采用了带有伽马和对数链接族的广义线性模型来分析医疗成本,并使用负二项回归分析医疗保健利用情况。在调整年龄、性别和合并症后,对心脏病、新冠诊断以及种族和族裔类别进行了三向交互分析。作者报告了平均边际效应及95%置信区间。
在1,008,166名医疗补助受益人中,2021年有8%患有心脏病。2021年每位受益人与心脏病相关的成本为10,819美元(95%置信区间=10,292;11,34