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顺铂、丝裂霉素C和5-氟尿嘧啶联合化疗治愈晚期胃癌

Cure of advanced gastric cancer by combined chemotherapy with cisplatinum, mitomycin C, and 5-fluorouracil.

作者信息

Tanemura H, Kawata R, Suzuki M, Shimokawa K, Azuma S, Furuta T, Saji S, Ohashi H, Sakata K

机构信息

Second Department of Surgery, Gifu University School of Medicine, Japan.

出版信息

J Surg Oncol. 1988 May;38(1):26-32. doi: 10.1002/jso.2930380109.

DOI:10.1002/jso.2930380109
PMID:3131592
Abstract

A 55-year-old female, in which an unresectable Borrmann II-type gastric cancer (moderately differentiated adenocarcinoma) extending from vicinity of the cardia to the lower portion of the corpus, with direct invasion into the pancreas and extensive lymph node metastases, confirmed by laparotomy, was treated postoperatively by 3 courses of chemotherapy with cisplatinum in combination with mitomycin C and 5-fluorouracil. A complete response was confirmed by roentgenography and endoscopy, and, at 4 months after the first operation, a total gastrectomy with radical lymphadenectomy was performed successfully. Cancer cells were not detectable histologically in the stomach specimen and in all the lymph nodes removed. One year and 5 months after the second operation she is well, showing no sign of recurrence.

摘要

一名55岁女性,经剖腹探查证实患有无法切除的Borrmann II型胃癌(中分化腺癌),肿瘤从贲门附近延伸至胃体下部,直接侵犯胰腺并伴有广泛淋巴结转移。术后接受了3个疗程的顺铂联合丝裂霉素C和5-氟尿嘧啶化疗。经X线检查和内镜检查确认完全缓解,首次手术后4个月成功进行了全胃切除术及根治性淋巴结清扫术。胃标本和所有切除的淋巴结在组织学上均未检测到癌细胞。第二次手术后1年零5个月,她情况良好,无复发迹象。

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Cure of advanced gastric cancer by combined chemotherapy with cisplatinum, mitomycin C, and 5-fluorouracil.顺铂、丝裂霉素C和5-氟尿嘧啶联合化疗治愈晚期胃癌
J Surg Oncol. 1988 May;38(1):26-32. doi: 10.1002/jso.2930380109.
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