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多柔比星-异环磷酰胺疗法有效治疗恶性乳腺叶状肿瘤

Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy.

作者信息

Yamamoto Shinya, Yamagishi Shigeru, Kohno Toshiro, Tajiri Ryosuke, Gondo Toshikazu, Yoshimoto Noboru, Kusano Nobuko

机构信息

Department of Breast Surgery, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa City, Kanagawa 251-8550, Japan.

Shonan Fujisawa Clinic, 1-15 Hanazawa-cho, Kugenuma, Fujisawa City, Kanagawa 251-0023, Japan.

出版信息

Case Rep Oncol Med. 2019 Jun 18;2019:2759650. doi: 10.1155/2019/2759650. eCollection 2019.

DOI:10.1155/2019/2759650
PMID:31316848
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6604495/
Abstract

Malignant phyllodes tumors of the breast occur infrequently and are difficult to treat with chemotherapy. Here, we present an effective chemotherapy strategy for recurrent malignant breast phyllodes tumors. A 48-year-old woman was diagnosed with a malignant phyllodes tumor in her right breast and underwent total right mastectomy. One year later, the tumor recurred in the right (a 2.2 cm mass) and left (a 10 cm mass) lungs; pleural effusion was also observed in the left lung. Eight courses of doxorubicin-ifosfamide (AI) therapy were administered. After treatment, the right lung mass and pleural effusion regressed completely and the left lung mass regressed to 2 cm. In conclusion, AI therapy is useful for treating recurrent malignant breast phyllodes tumors.

摘要

乳腺恶性叶状肿瘤发病率低，且化疗难以治疗。在此，我们提出一种针对复发性乳腺恶性叶状肿瘤的有效化疗策略。一名48岁女性被诊断出右乳患有恶性叶状肿瘤，并接受了右侧全乳切除术。一年后，肿瘤在右肺（一个2.2厘米的肿块）和左肺（一个10厘米的肿块）复发；左肺还观察到胸腔积液。给予了8个疗程的阿霉素-异环磷酰胺（AI）治疗。治疗后，右肺肿块和胸腔积液完全消退，左肺肿块缩小至2厘米。总之，AI治疗对复发性乳腺恶性叶状肿瘤有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/81689952c7fc/CRIONM2019-2759650.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/9f4c77ba7f17/CRIONM2019-2759650.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/8cde3ca841ab/CRIONM2019-2759650.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/ab2b3578ef06/CRIONM2019-2759650.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/089d547f9f2f/CRIONM2019-2759650.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/6c8b0dbb171c/CRIONM2019-2759650.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/81689952c7fc/CRIONM2019-2759650.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/9f4c77ba7f17/CRIONM2019-2759650.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/8cde3ca841ab/CRIONM2019-2759650.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/ab2b3578ef06/CRIONM2019-2759650.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/089d547f9f2f/CRIONM2019-2759650.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/6c8b0dbb171c/CRIONM2019-2759650.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0744/6604495/81689952c7fc/CRIONM2019-2759650.006.jpg

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