Department of Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Tuberculosis and Lung Disease Research Center, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Infect Disord Drug Targets. 2020;20(5):667-671. doi: 10.2174/1871526519666190715142100.
Planning for control of tuberculosis would need to screen and identify individuals susceptible to TB. Due to the weakness of immune system in diabetic patients, it is more likely for them to reactivate latent TB infection. Regarding the increasing number of diabetics in the community, in this study efforts have been made to estimate the frequency of individuals who have tuberculosis and diabetes mellitus (TB-DM) simultaneously, as it could help making preventive decisions to reduce TB in this part of Iran.
In this study, 329 cases of confirmed TB patients were divided into two groups of diabetic and non-diabetic, then demographic information and clinical variables have been compared between the two groups.
Among the examined subjects, 47 patients (14.29 %) had suffered from diabetes mellitus and tuberculosis. All of the DM patients had pulmonary tuberculosis and 87.23% of them were over the age of 50.
Majority of DM-TB patients were over 50 years of age and also more than half of them were women. So it seems that for DM women over the age of 50, to detect tuberculosis, screening tests such as PPD may be necessary.
结核病控制规划需要筛选和识别易患结核病的个体。由于糖尿病患者的免疫系统较弱，他们更有可能使潜伏性结核感染复发。鉴于社区中糖尿病患者的数量不断增加，本研究旨在估计同时患有结核病和糖尿病（TB-DM）的个体的频率，因为这有助于做出预防决策，以减少伊朗这一地区的结核病。
在这项研究中，将 329 例确诊结核病患者分为糖尿病组和非糖尿病组，然后比较两组之间的人口统计学信息和临床变量。
在所检查的对象中，有 47 名（14.29%）患有糖尿病和结核病。所有 DM 患者均患有肺结核，其中 87.23%的患者年龄在 50 岁以上。
大多数 DM-TB 患者年龄在 50 岁以上，其中超过一半是女性。因此，对于 50 岁以上的 DM 女性，可能需要进行 PPD 等筛查试验来检测结核病。
