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测量滑膜生物标志物在诊断感染性全踝关节置换术(TAA)中的作用如何?

Is There a Role for Measuring Synovial Biomarkers for Diagnosis of Infected Total Ankle Arthroplasty (TAA)?

机构信息

1 Ain Shams University Hospitals, Cairo, Egypt.

2 University of Manitoba, Winnipeg, MB, Canada.

出版信息

Foot Ankle Int. 2019 Jul;40(1_suppl):27S-29S. doi: 10.1177/1071100719859570.

Abstract

RECOMMENDATION

Based on the hip and knee arthroplasty literature, measuring synovial biomarkers may play a role in the diagnosis of infected total ankle arthroplasty (TAA). The diagnosis of periprosthetic joint infection (PJI) in the setting of a TAA can be confirmed with cultures, provided that a plausible pathogen is recovered in the context of a compatible clinical picture. In the absence of a positive culture, synovial biomarker analysis may help in establishing the diagnosis.

LEVEL OF EVIDENCE

Moderate.

DELEGATE VOTE

Agree: 92%, Disagree: 8%, Abstain: 0% (Super Majority, Strong Consensus).

摘要

建议

根据髋关节和膝关节置换术文献,测量滑液生物标志物可能有助于诊断感染性全踝关节置换术(TAA)。如果在具有相容临床特征的情况下从假体周围关节感染(PJI)中获得了合理的病原体,那么可以通过培养来确认 TAA 中的 PJI 诊断。如果培养结果为阴性,那么滑膜生物标志物分析可能有助于诊断。

证据等级

中等。

代表投票

同意:92%,不同意:8%,弃权:0%(超级多数,强烈共识)。

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