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感染性全踝关节置换术(TAA)的诊断“算法”是什么?

What Is the Diagnostic "Algorithm" for Infected Total Ankle Arthroplasty (TAA)?

机构信息

1 Department of Orthopaedics, The Royal London Hospital, Barts Health NHS Trust, London, United Kingdom.

2 Department of Orthopaedics and Rehabilitation University of Rochester, Rochester, NY, USA.

出版信息

Foot Ankle Int. 2019 Jul;40(1_suppl):21S-22S. doi: 10.1177/1071100719859536.

Abstract

RECOMMENDATION

Patients who present with clinical symptoms and signs of periprosthetic ankle infection (pain, erythema, warmth, sinus tract, abscess around the wound) and sinus tracts communicating with the ankle/subtalar joint are likely to have total ankle arthroplasty (TAA) infection. In the absence of a sinus tract, elevated inflammatory markers (erythrocyte sedimentation rate [ESR] and C-reactive protein [CRP]) should prompt ankle joint aspiration for cell count, differential, and culture. The joint aspiration is to be repeated. If the same organism is identified in at least 2 cultures of synovial fluid, the patient is diagnosed to have an infection. If the repeat aspiration is negative, further investigation is warranted. In patients not requiring operative intervention for other reasons, nuclear imaging should be considered for diagnosis. If an operation is indicated, histologic examination (>5 neutrophils/high-power field) or synovial fluid analysis is conducted to confirm infection.

LEVEL OF EVIDENCE

Limited.

DELEGATE VOTE

Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus).

摘要

建议

出现假体周围踝关节感染的临床症状和体征(疼痛、红斑、发热、窦道、伤口周围脓肿)和与踝关节/距下关节相通的窦道的患者可能患有全踝关节置换术(TAA)感染。在没有窦道的情况下,炎症标志物(红细胞沉降率[ESR]和 C 反应蛋白[CRP])升高应促使进行踝关节抽吸以进行细胞计数、分类和培养。应重复关节抽吸。如果在至少 2 份滑液培养物中都鉴定出相同的病原体,则诊断为感染。如果重复抽吸为阴性,则需要进一步检查。对于因其他原因不需要手术干预的患者,应考虑进行核成像以进行诊断。如果需要手术,进行组织学检查(>5 个中性粒细胞/高倍视野)或滑液分析以确认感染。

证据级别

有限。

代表投票

同意:100%,不同意:0%,弃权:0%(一致,最强共识)。

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