Xiao Y, Luo H W, Wu J, Zhang W L, Wang Y X
Department of OtolaryngologyHead and Neck Surgery, the First Hospital of Nanping, Fujian Medical University, Nanping, 353000, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jul;33(7):607-610. doi: 10.13201/j.issn.1001-1781.2019.07.008.
To investigate the clinical characteristics of non-eosinophilic and eosinophilic chronic sinusitis with nasal polyps.Ninty-two patients with chronic sinusitis with nasal polyps were collected and divided into eosinophilic chronic sinusitis with nasal polyps(EOS CRSwNP) and non-eosinophilic chronic sinusitis with nasal polyps(NONEOS CRSwNP) by pathological classification. The clinical characteristics between the two types were compared. NONEOS CRSwNP is more common in northern area of Fujian province(84.8%). NONEOS CRSwNP had the following clinical characteristics: one most nasal discharge was purulent; two more pyocysts can be seen in nasal polyps; three the proportion of eosinophils in the peripheral blood was mostly normal. Four mainly maxillary sinus lesions. EOS CRSwNP had the following characteristics: one most nasal discharge was mucous purulent; two bilateral sinus lesions were more common, mainly ethmoid sinus lesions; three the proportion of blood eosinophilic cells in peripheral blood was often increased. Ouroften accompanied by asthma, postoperative nasal polyps are prone to relapse, systemic steroid hormone is effective in the treatment of recurrent polyps.There are differences in clinical characteristics between eosinophilic and non-eosinophilic chronic sinusitis with nasal polyps. The ratio of eosinophils in peripheral blood, preoperative endoscopy and CT evaluation are helpful for the classification of chronic sinusitis with nasal polyps.
探讨非嗜酸性粒细胞性和嗜酸性粒细胞性鼻息肉慢性鼻窦炎的临床特征。收集92例鼻息肉慢性鼻窦炎患者，通过病理分类将其分为嗜酸性粒细胞性鼻息肉慢性鼻窦炎（EOS CRSwNP）和非嗜酸性粒细胞性鼻息肉慢性鼻窦炎（NONEOS CRSwNP）。比较两种类型之间的临床特征。NONEOS CRSwNP在福建省北部地区更为常见（84.8%）。NONEOS CRSwNP具有以下临床特征：一是多数鼻分泌物为脓性；二是鼻息肉中可见更多脓性囊肿；三是外周血中嗜酸性粒细胞比例大多正常。四是以主要上颌窦病变为主。EOS CRSwNP具有以下特征：一是多数鼻分泌物为黏液脓性；二是双侧鼻窦病变更为常见，主要为筛窦病变；三是外周血中嗜酸性粒细胞比例常升高。四是常伴有哮喘，术后鼻息肉易复发，全身使用类固醇激素对复发性息肉治疗有效。嗜酸性粒细胞性和非嗜酸性粒细胞性鼻息肉慢性鼻窦炎在临床特征上存在差异。外周血嗜酸性粒细胞比例、术前内镜检查和CT评估有助于鼻息肉慢性鼻窦炎的分类。
