检测西印度群岛格林纳达的褐家鼠（）中针对 spp. 的血清抗体。
Detection of serum antibodies against spp. in brown rats () from Grenada, West Indies.
作者信息
Sharma Ravindra Nath, Thille Katelyn, Piechowski Brianna, Tiwari Keshaw
机构信息
Department of Pathobiology, School of Veterinary Medicine, St. George's University, Grenada, West Indies.
出版信息
Vet World. 2019 May;12(5):696-699. doi: 10.14202/vetworld.2019.696-699. Epub 2019 May 23.
BACKGROUND AND AIM
Leptospirosis is an emerging disease of animals and humans. Among rodents brown rats () are an important reservoir of bacteria . There is a paucity of information on reservoirs of in Grenada. This study was conducted to estimate the prevalence of antibodies against spp. in brown rats in a densely human populated area of Grenada.
MATERIALS AND METHODS
Blood samples from 169 brown rats were collected and sera screened for antibodies against spp. using enzyme-linked immunosorbent assay.
RESULTS
Among a total of 169 brown rats trapped in two parishes in Grenada, 77/169 (45.5%) were positive for spp. antibodies. A significant difference in seropositive population of brown rats between two collection sites was observed. No differences were found between sex and age of seropositive rats.
CONCLUSION
Due to the close contact of brown rats with humans in Grenada, rats should be considered a high-risk factor in transmission of to humans. Appropriate preventive measures should be instituted to prevent the transmission of infection to humans.
背景与目的
钩端螺旋体病是一种在动物和人类中出现的疾病。在啮齿动物中，褐家鼠（）是该细菌的重要宿主。格林纳达关于该病菌宿主的信息匮乏。本研究旨在估计格林纳达人口密集地区褐家鼠中抗钩端螺旋体属物种抗体的流行率。
材料与方法
采集了169只褐家鼠的血样，并使用酶联免疫吸附测定法筛选血清中抗钩端螺旋体属物种的抗体。
结果
在格林纳达两个教区捕获的总共169只褐家鼠中，77/169（45.5%）的钩端螺旋体属物种抗体呈阳性。观察到两个采集地点褐家鼠血清阳性群体存在显著差异。血清阳性大鼠的性别和年龄之间未发现差异。
结论
由于格林纳达褐家鼠与人类密切接触，应将鼠类视为钩端螺旋体病传播给人类的高风险因素。应采取适当的预防措施以防止钩端螺旋体感染传播给人类。
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