Christakis Ioannis, Klang Patrick, Talat Nadia, Galata Gabriele, Schulte Klaus-Martin
Department of Endocrine Surgery, King's College Hospital NHS Foundation Trust, Brixton, London, UK.
Gland Surg. 2019 Jun;8(3):226-236. doi: 10.21037/gs.2018.09.02.
Vocal cord (VC) palsy following a thyroidectomy or parathyroidectomy can result in significant morbidity for the patient. We aimed to investigate the incidence of VC palsy in a tertiary referral Institution, track the management of these cases and record the long-term outcomes and VC recovery rates.
Retrospective review of all thyroidectomy/parathyroidectomy operations performed over 11 years. Patients with an unequivocal hoarse voice postoperatively were included. We analysed the patient's clinical characteristics and voice outcomes, operative, pathology and laryngoscopy reports during their follow-up.
Ten patients fitted the inclusion criteria and were analysed. Median age at date of operation was 47.5 years (range, 16-81 years) and the M:F ratio was 1:2.3 (M:3, F:7). The median FU was 62.5 months (range, 12-144 months). The median hospital stay was 1.5 days (range, 1-87 days). There were 7 recurrent laryngeal nerve (RLN) injuries by manipulation, 1 case of RLN resection, 1 inadvertent division (with primary nerve repair) and 1 RLN was shaved off the thyroid. Long-term voice outcomes for the 7 patients with an RLN manipulation injury were: 3/7 patients had normal voice, 3/7 had moderate hoarseness and 1/7 had long-term hoarseness. The long-term voice outcome of the patient with RLN shaving off the thyroid gland was excellent while the 2 remaining patients (RLN resection and inadvertent division) needed 12 and 18 months respectively to achieve a normal quality of voice. Four out of the 10 patients had permanent VC palsy in the long-term and their voice outcomes varied: 1 patient had a normal voice, 2 patients had moderate hoarseness and 1 patient had persistent hoarseness. Only 1/10 patients did not show any voice improvement after 12 months.
In the vast majority of cases post-operative hoarseness due to RLN palsy improves in the long-term, albeit voice may not return completely to normal.
甲状腺切除术或甲状旁腺切除术后的声带麻痹会给患者带来严重的发病风险。我们旨在调查一家三级转诊机构中声带麻痹的发生率,追踪这些病例的治疗情况,并记录长期预后和声带恢复率。
对11年间进行的所有甲状腺切除术/甲状旁腺切除术进行回顾性研究。纳入术后出现明确声音嘶哑的患者。我们分析了患者的临床特征、声音预后、手术、病理及随访期间的喉镜检查报告。
10例患者符合纳入标准并进行了分析。手术时的中位年龄为47.5岁(范围16 - 81岁),男女比例为1:2.3(男3例,女7例)。中位随访时间为62.5个月(范围12 - 144个月)。中位住院时间为1.5天(范围1 - 87天)。有7例因操作导致喉返神经(RLN)损伤,1例RLN切除,1例意外切断(进行了一期神经修复),1例RLN从甲状腺上剥离。7例因RLN操作损伤患者的长期声音预后为:3/7患者声音正常,3/7患者中度嘶哑,1/7患者长期嘶哑。RLN从甲状腺上剥离的患者长期声音预后良好,其余2例患者(RLN切除和意外切断)分别需要12个月和18个月才能恢复正常音质。10例患者中有4例长期存在永久性声带麻痹,其声音预后各不相同:1例患者声音正常,2例患者中度嘶哑,1例患者持续嘶哑。10例患者中只有1例在12个月后声音没有改善。
在绝大多数情况下,因RLN麻痹导致的术后声音嘶哑在长期内会有所改善,尽管声音可能不会完全恢复正常。