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院内心搏骤停复苏的早期终止与结局计算的影响。

Early termination of resuscitation in in-hospital cardiac arrest and impact to the outcome calculations.

机构信息

Medical School, Tampere University, Tampere, Finland.

Department of Emergency, Anaesthesia and Pain Medicine, Tampere University Hospital, Tampere, Finland.

出版信息

Acta Anaesthesiol Scand. 2019 Oct;63(9):1239-1245. doi: 10.1111/aas.13427. Epub 2019 Jul 21.

Abstract

BACKGROUND

Some in-hospital resuscitation attempts are assessed futile and terminated early on. We hypothesized that if these cases are reported separately, the true outcome of in-hospital cardiac arrest is better reflected.

METHODS

We conducted a 3-year prospective observational Utstein-style study in Tampere, Finland. All adult in-hospital cardiac arrests outside critical care areas attended by hospital's rapid response team were included. Resuscitation attempts that were terminated within 10 minutes were considered early terminations.

RESULTS

The cohort consisted of 199 in-hospital cardiac arrest patients. Twenty-seven (14%) resuscitation attempts were terminated early due to the presumed futility of the attempt with median resuscitation duration of 5 (4, 7) minutes. These cases and the 172 patients with full resuscitation attempt were of comparable age, sex and comorbidity. Early terminated resuscitation attempts were more often unwitnessed (63% vs. 10%, P < .001) with initial non-shockable rhythm (100% vs. 80%, P = .006) when compared with full attempts. The most frequently reported reasons for termination decisions were non-witnessed arrest presenting asystole as initial rhythm and severe acute illness. The hospital survival with good neurological outcome and 1-year survival were 30% and 25% for the whole cohort, and 34% and 29% when early terminated resuscitation attempts were excluded.

CONCLUSION

One-seventh of resuscitation attempts were terminated early on due to presumed futility of the attempt. Short- and long-term outcomes were 5% and 4% better when early terminated attempts were excluded from the outcome analyses. We believe that in-hospital cardiac arrest outcome is not as poor as repeatedly presented in the literature.

摘要

背景

有些院内复苏尝试被评估为无效,并在早期终止。我们假设,如果将这些病例单独报告,将更好地反映院内心脏骤停的真实结局。

方法

我们在芬兰坦佩雷进行了一项为期 3 年的前瞻性观察性乌斯丁式研究。所有在重症监护室外由医院快速反应小组救治的成年院内心脏骤停患者均纳入研究。在 10 分钟内终止的复苏尝试被认为是早期终止。

结果

该队列包括 199 例院内心脏骤停患者。27 例(14%)复苏尝试因尝试被认为无效而早期终止,中位复苏持续时间为 5(4,7)分钟。这些病例和 172 例进行了完整复苏尝试的患者在年龄、性别和合并症方面具有可比性。与完整的复苏尝试相比,早期终止的复苏尝试更常发生无目击者(63%比 10%,P<.001),初始非除颤性节律(100%比 80%,P=.006)。终止决策最常报告的原因是无目击者的心脏骤停表现为初始节律的停搏和严重的急性疾病。全队列的医院存活率和良好的神经功能预后 1 年存活率分别为 30%和 25%,当排除早期终止的复苏尝试时,分别为 34%和 29%。

结论

由于尝试无效,约七分之一的复苏尝试在早期被终止。当从结果分析中排除早期终止的尝试时,短期和长期结果分别提高了 5%和 4%。我们认为,院内心脏骤停的结局并不像文献中反复报道的那样差。

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