早发性结直肠癌：报告的统计数据能告诉我们什么，不能告诉我们什么，以及其影响。
Early-onset colorectal cancer: What reported statistics can and cannot tell us and their implications.
机构信息
Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
出版信息
Cancer. 2019 Nov 1;125(21):3706-3708. doi: 10.1002/cncr.32346. Epub 2019 Jul 22.
Abstract
In their current article, Virostko and colleagues report on the distribution of adult colorectal cancer cases in the National Cancer Database from 2004 to 2015 based on age-eligibility for screening. The editorial discusses the findings, the features of the database, and uses population-based data to contextualize emerging trends in incidence and mortality and the need for research to improve outcomes in all people at risk for colorectal cancer irrespective of screening-eligibility.
摘要
在他们目前的文章中，Virostko 及其同事根据筛查的年龄资格，报告了 2004 年至 2015 年国家癌症数据库中成年结直肠癌病例的分布情况。社论讨论了研究结果、数据库的特点，并利用基于人群的数据来了解发病率和死亡率的新趋势，以及需要开展研究来改善所有结直肠癌高危人群的预后，而不论其是否有资格进行筛查。
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本文引用的文献
1
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Cancer. 2019 Nov 1;125(21):3828-3835. doi: 10.1002/cncr.32347. Epub 2019 Jul 22.
2
Cost-Effectiveness and National Effects of Initiating Colorectal Cancer Screening for Average-Risk Persons at Age 45 Years Instead of 50 Years.45 岁而非 50 岁开始对一般风险人群进行结直肠癌筛查的成本效益和国家影响。
Gastroenterology. 2019 Jul;157(1):137-148. doi: 10.1053/j.gastro.2019.03.023. Epub 2019 Mar 28.
3
Effects of Organized Colorectal Cancer Screening on Cancer Incidence and Mortality in a Large Community-Based Population.基于大型社区人群的结直肠癌筛查对癌症发病率和死亡率的影响。
Gastroenterology. 2018 Nov;155(5):1383-1391.e5. doi: 10.1053/j.gastro.2018.07.017. Epub 2018 Jul 19.
4
Using the National Cancer Database for Outcomes Research: A Review.利用国家癌症数据库进行结果研究：综述。
JAMA Oncol. 2017 Dec 1;3(12):1722-1728. doi: 10.1001/jamaoncol.2016.6905.
5
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Cancer Epidemiol Biomarkers Prev. 2015 Aug;24(8):1151-6. doi: 10.1158/1055-9965.EPI-15-0082. Epub 2015 Jul 8.
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J Clin Oncol. 2015 Jun 20;33(18):2084-91. doi: 10.1200/JCO.2014.59.3665. Epub 2015 May 4.
7
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