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Rethinking the role of the brain in glucose homeostasis and diabetes pathogenesis.

作者信息

Brown Jenny M, Scarlett Jarrad M, Schwartz Michael W

机构信息

University of Washington Medicine Diabetes Institute, Department of Medicine, and.

Department of Pediatric Gastroenterology and Hepatology, University of Washington, Seattle, Washington, USA.

出版信息

J Clin Invest. 2019 Jul 22;129(8):3035-3037. doi: 10.1172/JCI130904.

DOI:10.1172/JCI130904
PMID:31329157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6668663/
Abstract
摘要

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Central and Peripheral Administration of Fibroblast Growth Factor 1 Improves Pancreatic Islet Insulin Secretion in Diabetic Mouse Models.成纤维细胞生长因子 1 中枢和外周给药改善糖尿病小鼠模型胰岛胰岛素分泌。
Diabetes. 2019 Jul;68(7):1462-1472. doi: 10.2337/db18-1175. Epub 2019 May 2.
2
The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1.成纤维细胞生长因子 1 可诱导持续缓解糖尿病，其作用靶点为下丘脑弓状核-正中隆起。
Diabetes. 2019 May;68(5):1054-1061. doi: 10.2337/db19-0025. Epub 2019 Feb 22.
3
New Neuroscience of Homeostasis and Drives for Food, Water, and Salt.新稳态神经科学与食物、水和盐的驱动力
N Engl J Med. 2019 Jan 31;380(5):459-471. doi: 10.1056/NEJMra1812053.
4
Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain.介导脑内 FGF1 持续抗糖尿病作用的外周机制。
Diabetes. 2019 Mar;68(3):654-664. doi: 10.2337/db18-0498. Epub 2018 Dec 6.
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Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects.下丘脑腹内侧核的不同神经元投射介导血糖和行为效应。
Diabetes. 2018 Dec;67(12):2518-2529. doi: 10.2337/db18-0380. Epub 2018 Sep 26.
6
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