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由主动脉专科医生实施的急性A型主动脉夹层手术可改善2年预后。

Acute Type A Aortic Dissection Surgery Performed by Aortic Specialists Improves 2-Year Outcomes.

作者信息

Bin Mahmood Syed Usman, Mori Makoto, Geirsson Arnar, Elefteriades John A, Mangi Abeel A

机构信息

Section of Cardiac Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.

出版信息

Aorta (Stamford). 2019 Feb;7(1):1-6. doi: 10.1055/s-0039-1687904. Epub 2019 Jul 22.

DOI:10.1055/s-0039-1687904
PMID:31330545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6645905/
Abstract

OBJECTIVE

In patients presenting with acute Type A aortic dissections (ATADs), the authors sought to evaluate whether emergent aortic operations performed by cardiac surgeons with different level of aortic surgery experience can impact perioperative outcomes and survival.

METHODS

A single-center review of 102 patients who underwent aortic surgeries for ATAD was conducted. The cohort was divided into those operated on by aortic specialists (AS:3 surgeons) and non-AS (5 surgeons). Multivariable logistic regression and Cox proportional hazard models were fitted to evaluate associations between the surgeon experience, perioperative outcomes, and survival, respectively.

RESULTS

Of 102 patients, 60 were operated on by AS and 42 were operated on by non-AS. Overall 30-day mortality was 11 (10.8%) with 4 (6.6%) perioperative deaths in the AS group and 7 (16.6%) among the non-AS group ( = 0.2). AS performed a significantly higher number of root replacement procedures (41.6% vs. 23.8%, respectively,  = 0.049) and employed more frequent adjunct cerebral perfusion during circulatory arrest ( = 0.003). Survival analysis indicated AS status was an independent predictor of improved 2-year survival (hazard ratio: 0.37, 95% confidence interval: 0.15-0.92,  = 0.03).

CONCLUSION

Operation by AS for ATAD was associated with reduced adjusted risk of 2-year mortality. This adds support for establishing thoracic aortic emergency call teams staffed by AS.

摘要

目的

在患有急性A型主动脉夹层(ATAD)的患者中,作者试图评估由具有不同主动脉手术经验水平的心脏外科医生进行的急诊主动脉手术是否会影响围手术期结果和生存率。

方法

对102例行主动脉手术治疗ATAD的患者进行单中心回顾性研究。该队列分为由主动脉专科医生(AS:3名外科医生)和非AS(5名外科医生)进行手术的两组。分别采用多变量逻辑回归和Cox比例风险模型来评估外科医生经验、围手术期结果和生存率之间的关联。

结果

102例患者中,60例由AS进行手术,42例由非AS进行手术。总体30天死亡率为11例(10.8%),AS组围手术期死亡4例(6.6%),非AS组7例(16.6%)(P = 0.2)。AS进行根部置换手术的数量明显更多(分别为41.6%和23.8%,P = 0.049),并且在循环停止期间更频繁地采用辅助脑灌注(P = 0.003)。生存分析表明,AS状态是改善2年生存率的独立预测因素(风险比:0.37,95%置信区间:0.15 - 0.92,P = 0.03)。

结论

由AS进行ATAD手术与降低2年调整后死亡风险相关。这为组建由AS人员组成的胸主动脉急诊呼叫团队提供了支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7779/6645905/d8f1036329c3/10-1055-s-0039-1687904-i180044-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7779/6645905/d8f1036329c3/10-1055-s-0039-1687904-i180044-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7779/6645905/d8f1036329c3/10-1055-s-0039-1687904-i180044-1.jpg

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