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降结肠原发性弥漫性大 B 细胞淋巴瘤。

Primary Diffuse Large B-Cell Lymphoma of the Descending Colon.

机构信息

Division of Internal Medicine, Department of Medicine, SUNY Upstate Medical University, Syracuse, New York.

Division of Gastroenterology, Department of Medicine, SUNY Upstate Medical University, Syracuse, New York.

出版信息

Am J Med Sci. 2019 Aug;358(2):164-167. doi: 10.1016/j.amjms.2019.05.004. Epub 2019 May 23.

Abstract

Primary non-Hodgkin lymphoma of the gastrointestinal tract is rare with an incidence of 10-15% of all non-Hodgkin lymphoma cases and 1-4% of all gastrointestinal tumors. The most common sites of involvement include the stomach, small intestines, colon and rectum. Primary colorectal lymphoma is extremely rare representing only 0.2-0.6% of all colorectal malignancies. The presentation is usually non-specific leading to delay in diagnosis. Imaging is used to locate the tumor and its extension. Colonoscopy usually shows a fungating mass, infiltrative or ulcerative lesion. Diffuse large B-cell lymphoma is the most common histological subtype. Management of diffuse large B-cell lymphoma usually involves chemotherapy, radiation, surgery or a combination approach.

摘要

胃肠道原发性非霍奇金淋巴瘤较为罕见,占所有非霍奇金淋巴瘤病例的 10-15%,占所有胃肠道肿瘤的 1-4%。最常见的受累部位包括胃、小肠、结肠和直肠。原发性结直肠淋巴瘤极为罕见,仅占所有结直肠恶性肿瘤的 0.2-0.6%。其表现通常不具特异性,导致诊断延迟。影像学用于定位肿瘤及其扩展。结肠镜检查通常显示出息肉样肿块、浸润性或溃疡性病变。弥漫性大 B 细胞淋巴瘤是最常见的组织学亚型。弥漫性大 B 细胞淋巴瘤的治疗通常包括化疗、放疗、手术或联合治疗。

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