Division of Internal Medicine, Department of Medicine, SUNY Upstate Medical University, Syracuse, New York.
Division of Gastroenterology, Department of Medicine, SUNY Upstate Medical University, Syracuse, New York.
Am J Med Sci. 2019 Aug;358(2):164-167. doi: 10.1016/j.amjms.2019.05.004. Epub 2019 May 23.
Primary non-Hodgkin lymphoma of the gastrointestinal tract is rare with an incidence of 10-15% of all non-Hodgkin lymphoma cases and 1-4% of all gastrointestinal tumors. The most common sites of involvement include the stomach, small intestines, colon and rectum. Primary colorectal lymphoma is extremely rare representing only 0.2-0.6% of all colorectal malignancies. The presentation is usually non-specific leading to delay in diagnosis. Imaging is used to locate the tumor and its extension. Colonoscopy usually shows a fungating mass, infiltrative or ulcerative lesion. Diffuse large B-cell lymphoma is the most common histological subtype. Management of diffuse large B-cell lymphoma usually involves chemotherapy, radiation, surgery or a combination approach.
胃肠道原发性非霍奇金淋巴瘤较为罕见，占所有非霍奇金淋巴瘤病例的 10-15%，占所有胃肠道肿瘤的 1-4%。最常见的受累部位包括胃、小肠、结肠和直肠。原发性结直肠淋巴瘤极为罕见，仅占所有结直肠恶性肿瘤的 0.2-0.6%。其表现通常不具特异性，导致诊断延迟。影像学用于定位肿瘤及其扩展。结肠镜检查通常显示出息肉样肿块、浸润性或溃疡性病变。弥漫性大 B 细胞淋巴瘤是最常见的组织学亚型。弥漫性大 B 细胞淋巴瘤的治疗通常包括化疗、放疗、手术或联合治疗。
