Qu Junchi, Zhuang Yanyan, Zheng Dandan, Huang Fengting, Zhang Shineng
Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, CHN.
Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, CHN.
Cureus. 2021 Sep 1;13(9):e17628. doi: 10.7759/cureus.17628. eCollection 2021 Sep.
Primary esophageal lymphoma is a rare malignant tumor, which is often misdiagnosed. To improve the diagnosis and treatment of this disease, we presented one case admitted at our institution and a literature review of primary esophageal lymphoma cases, including the clinical data, features of imaging, endoscopy and pathology, treatment, and prognosis. The symptoms were non-specific. Under endoscopy, most of the lesions were located in the middle and lower segment of the esophagus, behaving as ulcers, polyps, or submucosal masses, always accompanying with esophageal stricture. The diagnosis of primary esophageal lymphoma was highly dependent on pathological and immunohistochemical examination, hence stacked sampling was suggested to improve the positive rate of mucosal biopsy. Combination of chemotherapy and radiotherapy may be the first choice of treatment, surgical and endoscopic resections may be an alternative solution as well. The therapeutic effect and prognosis were slightly better than those of other esophageal malignant tumors.
原发性食管淋巴瘤是一种罕见的恶性肿瘤，常被误诊。为提高该病的诊断和治疗水平，我们报告了本院收治的1例病例，并对原发性食管淋巴瘤病例进行文献复习，内容包括临床资料、影像学、内镜及病理学特征、治疗及预后。其症状无特异性。内镜检查下，多数病变位于食管中下段，表现为溃疡、息肉或黏膜下肿块，常伴有食管狭窄。原发性食管淋巴瘤的诊断高度依赖病理及免疫组化检查，因此建议采用多点取材以提高黏膜活检的阳性率。化疗与放疗联合可能是首选治疗方法，手术及内镜切除也可作为替代方案。其治疗效果及预后略优于其他食管恶性肿瘤。
