Schneider T, Lange R, Niederhut D
Institut für Angewandte Zoologie, Berlin.
Dtsch Med Wochenschr. 1988 Jul 1;113(26):1061-3. doi: 10.1055/s-2008-1067767.
In November 1983 a woman born in 1902 was found to have thrombocytopenic purpura with a platelet count of 14,000/microliter. Examination of the sternal marrow resulted in a suspected diagnosis of Werlhof's disease. Platelet counts dropped at times to below 7,000/microliter during immunosuppressive treatment with corticosteroids and azathioprine of three months' duration. When this treatment was discontinued spontaneous remission occurred until July 1984. Acrodermatitis chronica atrophicans was diagnosed in August 1987. The IgG antibody titre against Borrelia burgdorferi of 1:2,000 in whole blood and the late manifestation of Lyme disease (chronic acrodermatitis atrophicans) suggest a causal relationship with the previous thrombocytopenic purpura.
1983年11月，一名1902年出生的女性被发现患有血小板减少性紫癜，血小板计数为14,000/微升。胸骨骨髓检查结果疑似诊断为韦尔霍夫病。在为期三个月的皮质类固醇和硫唑嘌呤免疫抑制治疗期间，血小板计数有时会降至7,000/微升以下。当停止这种治疗后，出现了自发缓解，直至1984年7月。1987年8月诊断为慢性萎缩性肢端皮炎。全血中抗伯氏疏螺旋体的IgG抗体滴度为1:2,000以及莱姆病的晚期表现（慢性萎缩性肢端皮炎）表明与先前的血小板减少性紫癜存在因果关系。
