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Clinical Significance of the Plasma Protein Binding of Rifampicin in the Treatment of Tuberculosis Patients.

作者信息

Verbeeck Roger K, Singu Bonifasius S, Kibuule Dan

机构信息

School of Pharmacy, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia.

出版信息

Clin Pharmacokinet. 2019 Dec;58(12):1511-1515. doi: 10.1007/s40262-019-00800-1.

DOI:10.1007/s40262-019-00800-1
PMID:31332668
Abstract
摘要

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Dosage of isoniazid and rifampicin poorly predicts drug exposure in tuberculosis patients.异烟肼和利福平的剂量不能很好地预测结核病患者的药物暴露情况。
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Why Do We Use 600 mg of Rifampicin in Tuberculosis Treatment?为什么结核病治疗中要使用 600 毫克利福平？
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Quality assurance of fixed-dose combinations of anti-tuberculosis medications. Proceedings of an IUATLD/WHO workshop, 29th IUATLD World Conference. Bangkok, Thailand, November 1998.抗结核药物固定剂量复方制剂的质量保证。国际防痨和肺部疾病联盟/世界卫生组织研讨会会议记录，第29届国际防痨和肺部疾病联盟世界会议。泰国曼谷，1998年11月。
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Clin Infect Dis. 2013 Aug;57(3):480-1. doi: 10.1093/cid/cit258. Epub 2013 Apr 24.
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Int J Tuberc Lung Dis. 2001 Sep;5(9):880-2.

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A hybrid model to evaluate the impact of active uptake transport on hepatic distribution of atorvastatin in rats.

本文引用的文献

1
Maturational changes in vancomycin protein binding affect vancomycin dosing in neonates.万古霉素蛋白结合的成熟变化影响新生儿万古霉素的给药剂量。
Br J Clin Pharmacol. 2019 May;85(5):865-867. doi: 10.1111/bcp.13899. Epub 2019 Mar 4.
2
Protein binding of rifampicin is not saturated when using high-dose rifampicin.利福平高剂量使用时蛋白结合并未达到饱和。
J Antimicrob Chemother. 2019 Apr 1;74(4):986-990. doi: 10.1093/jac/dky527.
3
Pharmacokinetic and Pharmacodynamic Considerations for Drugs Binding to Alpha-1-Acid Glycoprotein.
一种用于评估主动摄取转运对大鼠阿托伐他汀肝脏分布影响的混合模型。
Xenobiotica. 2020 May;50(5):536-544. doi: 10.1080/00498254.2019.1668982. Epub 2019 Oct 1.
药物与α-1-酸性糖蛋白结合的药代动力学和药效学考虑因素。
Pharm Res. 2018 Dec 28;36(2):30. doi: 10.1007/s11095-018-2551-x.
4
A Systematic Review on the Effect of HIV Infection on the Pharmacokinetics of First-Line Tuberculosis Drugs.HIV 感染对一线抗结核药物药代动力学影响的系统评价。
Clin Pharmacokinet. 2019 Jun;58(6):747-766. doi: 10.1007/s40262-018-0716-8.
5
Protein Binding of First-Line Antituberculosis Drugs.一线抗结核药物的蛋白结合率。
Antimicrob Agents Chemother. 2018 Jun 26;62(7). doi: 10.1128/AAC.00641-18. Print 2018 Jul.
6
Pharmacokinetics of rifampicin in adult TB patients and healthy volunteers: a systematic review and meta-analysis.利福平在成人结核病患者和健康志愿者中的药代动力学：系统评价和荟萃分析。
J Antimicrob Chemother. 2018 Sep 1;73(9):2305-2313. doi: 10.1093/jac/dky152.
7
Pharmacokinetics of the First-Line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with or without HIV Coinfection.一线抗结核药物在加纳合并或未合并HIV感染的结核病儿童中的药代动力学。
Antimicrob Agents Chemother. 2017 Jan 24;61(2). doi: 10.1128/AAC.01701-16. Print 2017 Feb.
8
The challenges of pharmacokinetic variability of first-line anti-TB drugs.一线抗结核药物药代动力学变异性的挑战。
Expert Rev Clin Pharmacol. 2017 Jan;10(1):47-58. doi: 10.1080/17512433.2017.1246179. Epub 2016 Nov 2.
9
Optimizing treatment outcome of first-line anti-tuberculosis drugs: the role of therapeutic drug monitoring.优化一线抗结核药物的治疗效果：治疗药物监测的作用
Eur J Clin Pharmacol. 2016 Aug;72(8):905-16. doi: 10.1007/s00228-016-2083-4. Epub 2016 Jun 15.
10
Low Serum Concentrations of Rifampicin and Pyrazinamide Associated with Poor Treatment Outcomes in Children with Tuberculosis Related to HIV Status.血清中利福平和平吡嗪酰胺浓度低与合并人类免疫缺陷病毒感染的儿童结核病治疗效果不佳相关。
Pediatr Infect Dis J. 2016 May;35(5):530-4. doi: 10.1097/INF.0000000000001069.