大肠杆菌的硫醇敏感启动子。
Thiol-sensitive promoters of Escherichia coli.
作者信息
Javor G T, Stringer C D, Ryu J
机构信息
Department of Microbiology, Loma Linda University School of Medicine, California 92350.
出版信息
J Bacteriol. 1988 Jul;170(7):3291-3. doi: 10.1128/jb.170.7.3291-3293.1988.
Abstract
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive promoters suggests that exogenous thiols may provoke global stress responses in E. coli.
摘要
分离出大肠杆菌CSH50的Mu dX(lac)插入突变体，其中lacZ基因的表达对外源1-硫代甘油或二硫苏糖醇的存在敏感。发现了刺激性和抑制性突变体。几种硫醇敏感启动子的存在表明外源硫醇可能在大肠杆菌中引发全局应激反应。
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