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术中使用吲哚菁绿血管造影术提高显微重建手术的安全性

Enhancing Safety in Reconstructive Microsurgery Using Intraoperative Indocyanine Green Angiography.

作者信息

Ludolph Ingo, Horch Raymund E, Arkudas Andreas, Schmitz Marweh

机构信息

Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen, Friedrich-Alexander-University of Erlangen-Nuernberg FAU, Erlangen, Germany.

出版信息

Front Surg. 2019 Jul 2;6:39. doi: 10.3389/fsurg.2019.00039. eCollection 2019.

Abstract

Intraoperative assessing and postoperative monitoring of the viability of free flaps is of high relevance in reconstructive microsurgery. Today different methods for the evaluation of tissue perfusion are known. Indocyanine Green angiography is an emerging technique among plastic surgeons with a broad scope of applications especially in microsurgical free flap transfer. We demonstrate the value and clinical application of this technique based on representative selected cases where Indocyanine Green angiography was used in microsurgical free flap transfers from different anatomic donor sites during the operation. Hereby perforator selection, flap tailoring, changes of blood flow and patency of anastomoses was judged and decision making was based on the angiographic findings. This method has proven to be valid, reproducible and easy to use. The application is not limited to the evaluation of skin perfusion, but is also applicable to muscle tissue or chimeric or composite flaps. Reliable judgement is especially given for the extent of arterially perfused tissue following complete flap dissection. Moreover, this real-time angiography revealed a high sensitivity for the detection of poorly perfused flap areas, thus supporting the conventional clinical judgement and reducing complications. In summary Indocyanine Green angiography has the potential to reduce flap related complications and to contribute to enhancing and extending the possibilities of free flap surgery.

摘要

在显微重建外科手术中,术中评估和术后监测游离皮瓣的存活能力至关重要。目前已知多种评估组织灌注的方法。吲哚菁绿血管造影术是整形外科医生中新兴的一项技术,其应用范围广泛,尤其在显微外科游离皮瓣移植中。我们基于具有代表性的选定病例展示了该技术的价值和临床应用,这些病例在手术过程中于不同解剖供区进行显微外科游离皮瓣移植时使用了吲哚菁绿血管造影术。据此判断穿支选择、皮瓣裁剪、血流变化以及吻合口通畅情况,并根据血管造影结果进行决策。该方法已被证明是有效、可重复且易于使用的。其应用不仅限于评估皮肤灌注,还适用于肌肉组织或嵌合或复合皮瓣。对于完全游离皮瓣后的动脉灌注组织范围,能给出可靠的判断。此外,这种实时血管造影术对检测灌注不良的皮瓣区域具有高灵敏度,从而支持传统的临床判断并减少并发症。总之,吲哚菁绿血管造影术有潜力减少与皮瓣相关的并发症,并有助于增强和扩展游离皮瓣手术的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b09b/6614526/10334f626e76/fsurg-06-00039-g0001.jpg

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