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Genome-wide association studies of atrial fibrillation: Finding meaning in the life of risk loci.

作者信息

Sutanto Henry, Dobrev Dobromir, Heijman Jordi

机构信息

Department of Cardiology, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands.

Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany.

出版信息

Int J Cardiol Heart Vasc. 2019 Jul 8;24:100397. doi: 10.1016/j.ijcha.2019.100397. eCollection 2019 Sep.

DOI:10.1016/j.ijcha.2019.100397
PMID:31334334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6617160/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a2/6617160/04c53a87b782/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a2/6617160/04c53a87b782/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a2/6617160/04c53a87b782/gr1.jpg

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and as Atrial Fibrillation Susceptibility Genes in the Chinese Population via Bioinformatics and Genome-Wide Association Analysis.以及通过生物信息学和全基因组关联分析确定中国人群中的心房颤动易感基因。
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本文引用的文献

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Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway.利用全基因组关联研究（GWAS）数据进行的通路分析检测到房颤与mTOR信号通路之间的关联。
Int J Cardiol Heart Vasc. 2019 Jul 4;24:100383. doi: 10.1016/j.ijcha.2019.100383. eCollection 2019 Sep.
2
Bayesian network analyses in atrial fibrillation - A path to better therapies?心房颤动中的贝叶斯网络分析——通向更好治疗方法的途径？
Int J Cardiol Heart Vasc. 2019 Mar 4;22:210-211. doi: 10.1016/j.ijcha.2019.02.009. eCollection 2019 Mar.
3
Antiarrhythmic drugs for atrial fibrillation: Imminent impulses are emerging.
PITX2上调通过调节……以剂量依赖方式增加慢性心房颤动风险——来自人体心房建模的见解 （原文中“modulating and -”表述不完整，可能影响准确理解和完整翻译）
Ann Transl Med. 2020 Mar;8(5):191. doi: 10.21037/atm.2020.01.90.
用于心房颤动的抗心律失常药物：即将出现新的进展。
Int J Cardiol Heart Vasc. 2018 Sep 13;21:11-15. doi: 10.1016/j.ijcha.2018.08.005. eCollection 2018 Dec.
4
Oral anticoagulant use for stroke prevention in atrial fibrillation patients with difficult scenarios.口服抗凝药在具有复杂情况的心房颤动患者中用于预防卒中。
Int J Cardiol Heart Vasc. 2018 Aug 31;20:56-62. doi: 10.1016/j.ijcha.2018.08.003. eCollection 2018 Sep.
5
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.生物银行驱动的基因组发现为心房颤动生物学提供了新的见解。
Nat Genet. 2018 Sep;50(9):1234-1239. doi: 10.1038/s41588-018-0171-3. Epub 2018 Jul 30.
6
The long-term efficacy of concomitant maze IV surgery in patients with atrial fibrillation.迷宫IV手术联合治疗心房颤动患者的长期疗效。
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Scientific Contributions of Population-Based Studies to Cardiovascular Epidemiology in the GWAS Era.基于人群的研究在全基因组关联研究时代对心血管流行病学的科学贡献。
Front Cardiovasc Med. 2018 Jun 7;5:57. doi: 10.3389/fcvm.2018.00057. eCollection 2018.
8
Multi-ethnic genome-wide association study for atrial fibrillation.多民族全基因组关联研究心房颤动。
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Age modifies the risk of atrial fibrillation among athletes: A systematic literature review and meta-analysis.年龄对运动员发生心房颤动的风险具有修饰作用：一项系统文献综述与荟萃分析。
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