Resistome and a Novel -Harboring Plasmid of an Strain from a Children's Hospital in Puebla, Mexico.

complex isolates have been frequently associated with hospital and community infections, with being the most common. Other spp. not belonging to this complex also cause infections in hospital settings, and the incidence has increased over the past few years. Some species of the genus possess a great diversity of antibiotic resistance mechanisms, such as efflux pumps, porins, and resistance genes that can be acquired and disseminated by mobilizable genetic elements. By means of whole-genome sequencing, we describe in the clinical strain AN54 different mechanisms of resistance that involve , , , , and a resistance-nodulation-cell division-type efflux pump. This strain carries six plasmids, of which the plasmid pAhaeAN54e contains in a Tn125-like transposon that is truncated at the 3' end. This strain also has an insertion sequence IS and seven genes encoding hypothetical proteins. The pAhaeAN54e plasmid is nontypable and different from other plasmids carrying that have been reported in Mexico and other countries. The presence of these kinds of plasmids in an opportunistic pathogen such as highlights the role that these plasmids play in the dissemination of antibiotic resistance genes, especially against carbapenems, in Mexican hospitals.