墨西哥城一家三级护理医院中，由携带NDM-1金属β-内酰胺酶的肠杆菌科细菌在IncFII质粒中传播引发的疫情。
Outbreak caused by Enterobacteriaceae harboring NDM-1 metallo-β-lactamase carried in an IncFII plasmid in a tertiary care hospital in Mexico City.
作者信息
Torres-González Pedro, Bobadilla-Del Valle Miriam, Tovar-Calderón Estrella, Leal-Vega Francisco, Hernández-Cruz Araceli, Martínez-Gamboa Areli, Niembro-Ortega María Dolores, Sifuentes-Osornio José, Ponce-de-León Alfredo
机构信息
Department of Infectious Diseases, Laboratory of Clinical Microbiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Department of Medicine, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
出版信息
Antimicrob Agents Chemother. 2015 Nov;59(11):7080-3. doi: 10.1128/AAC.00055-15. Epub 2015 Aug 17.
Abstract
Carbapenem-resistant Enterobacteriaceae carrying New Delhi metallo-β-lactamase 1 (NDM-1) have rarely been reported in Latin America. We report of an outbreak caused by a blaNDM-1-harboring plasmid spread through different bacterial species, including Escherichia coli (ST617) and Enterobacter cloacae (ST182) isolates from the same patient and three Klebsiella pneumoniae isolates (ST22) derived from three epidemiologically related patients. IncFII plasmids were found in all strains. Measures to control the outbreak were applied successfully.
摘要
携带新德里金属β-内酰胺酶1（NDM-1）的耐碳青霉烯类肠杆菌科细菌在拉丁美洲鲜有报道。我们报告了一起由携带blaNDM-1的质粒引起的暴发，该质粒在不同细菌物种中传播，包括来自同一患者的大肠杆菌（ST617）和阴沟肠杆菌（ST182）分离株，以及来自三名流行病学相关患者的三株肺炎克雷伯菌分离株（ST22）。所有菌株中均发现了IncFII质粒。成功采取了控制暴发的措施。
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