Calcaterra Valeria, Regalbuto Corrado, Madè Alexandra, Magistrali Mariasole, Leonard Maureen M, Cena Hellas
Pediatrics and Adolescentology Unit, Department of Internal Medicine, University of Pavia, Pavia, Italy.
Pediatric Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Pediatr Gastroenterol Hepatol Nutr. 2019 Jul;22(4):407-412. doi: 10.5223/pghn.2019.22.4.407. Epub 2019 Jun 18.
Excessive weight gain in children diagnosed with celiac disease (CD) is becoming more common. We describe 2 siblings (9-year and 6 months-old female and 6-year and 9 months-old male) with obesity showing attenuated gastrointestinal and atypical symptoms in which CD was diagnosed in the absence of a known family history of CD. After children's diagnosis, CD in their parents was also investigated. It was detected in their father affected by overweight. The presentation of patients with CD has changed. While patients with overweight and obesity commonly have symptoms such as abdominal pain, reflux, headache, and constipation due to lifestyle factors, CD should also be considered in patients with or without a family history of CD. Careful nutritional status assessment and follow-up monitoring after the diagnosis of CD are mandatory, especially in subjects who are already overweight at the presentation of this disease.
被诊断为乳糜泻（CD）的儿童体重过度增加正变得越来越普遍。我们描述了2名肥胖的兄弟姐妹（9岁6个月大的女性和6岁9个月大的男性），他们的胃肠道症状减轻且症状不典型，在没有已知CD家族史的情况下被诊断出患有CD。在儿童被诊断后，还对他们父母的CD情况进行了调查。在他们超重的父亲身上检测到了CD。CD患者的表现已经发生了变化。虽然超重和肥胖的患者通常因生活方式因素出现腹痛、反流、头痛和便秘等症状，但无论有无CD家族史的患者都应考虑CD的可能性。CD诊断后仔细的营养状况评估和随访监测是必不可少的，尤其是对于在该病初发时就已经超重的患者。
