Grassato Lisa, Drudi Dario, Pinna Stefania, Valentini Simona, Diana Alessia, Spinella Giuseppe
Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Clinica Veterinaria Nervianese, Nerviano, Italy.
Front Vet Sci. 2019 Jul 9;6:229. doi: 10.3389/fvets.2019.00229. eCollection 2019.
Forelimb lameness in medium and large breed dogs is frequently caused by traumatic or degenerative injuries of the shoulder. Patient history, physical examination, x-rays, blood, and chemical work are routinely used to achieve diagnosis, and may be associated with ultrasonography or magnetic resonance imaging. Ultrasonography is increasingly popular in small animal practice due to its low cost, ease of repetition, and the fact that it is non-invasive and can be performed in conscious patients. It is also widely accepted that muscular stress or injuries can induce detectable variations in blood and chemical work. The aim of this preliminary study is to search for correlation between measurements of selected hematobiochemical parameters and ultrasound diagnosis in dogs affected by shoulder injuries. A retrospective study was conducted on orthopedic clinical records of dogs presented to our Veterinary Teaching Hospital for lameness caused by shoulder problems over a period of 5 years. Dogs with both hematobiochemical and ultrasound examinations were selected. Patients were classified into 5 groups according to ultrasound diagnosis: (1) mild/moderate tendinopathy, (2) severe tendinopathy, (3) articular damage, (4) chronic myopathy, and (5) neoplastic injury. Statistical analysis was performed to detect possible correlations between group and hematobiochemical parameters. Forty-four dogs met the inclusion criteria and forty-nine shoulders were diagnosed as injured. Significant differences were found between the age, sex, body weight, neutrophil count, and AST levels. In particular, statistically significant increases were found for neutrophil count and AST concentration in case of ultrasonographically diagnosed severe tendinopathy, articular damage, and neoplastic pathology. Further and wider studies are suggested to determine whether these biomarkers can become a useful diagnostic aid.
中大型犬的前肢跛行通常由肩部的创伤性或退行性损伤引起。患者病史、体格检查、X光、血液和化学检查通常用于进行诊断，可能还会结合超声检查或磁共振成像。超声检查因其成本低、易于重复，且具有非侵入性且可在清醒患者身上进行的特点，在小动物临床实践中越来越受欢迎。人们也普遍认为，肌肉压力或损伤会在血液和化学检查中引起可检测到的变化。这项初步研究的目的是寻找受肩部损伤影响的犬只中选定血液生化参数测量值与超声诊断之间的相关性。对在5年期间因肩部问题导致跛行而被送到我们兽医教学医院的犬只的骨科临床记录进行了回顾性研究。选择了同时进行了血液生化和超声检查的犬只。根据超声诊断将患者分为5组：(1) 轻度/中度肌腱病，(2) 重度肌腱病，(3) 关节损伤，(4) 慢性肌病，(5) 肿瘤性损伤。进行了统计分析以检测组与血液生化参数之间可能的相关性。44只犬符合纳入标准，49个肩部被诊断为受伤。在年龄、性别、体重、中性粒细胞计数和AST水平之间发现了显著差异。特别是，在超声诊断为重度肌腱病、关节损伤和肿瘤性病变的情况下，中性粒细胞计数和AST浓度在统计学上有显著升高。建议进行进一步更广泛的研究，以确定这些生物标志物是否可以成为有用的诊断辅助手段。
