Wingate Institute of Neurogastroenterology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Health and Lifestyle Research Unit, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.
Aliment Pharmacol Ther. 2019 Sep;50(5):530-537. doi: 10.1111/apt.15417. Epub 2019 Jul 24.
Supragastric belching (SGB) has a significant behavioural component. We recently used cognitive behavioural therapy (CBT) to treat SGB. We demonstrated that CBT significantly reduces symptoms and improves quality of life in 50% of patients who had completed treatment.
To investigate factors associated with successful CBT for SGB and to assess symptoms 6-12 months after completion of CBT METHODS: Records of 39 patients who had completed the CBT protocol were analysed. Per cent pre- to post-treatment change in symptoms was assessed using a visual analogue scale (VAS) score. We evaluated the association between 'pre-treatment' factors and 'during-treatment' factors, and symptomatic outcomes. Symptoms were also assessed 6-12 months after treatment.
From 'pre-treatment factors', a lower number of SGBs (P < .01) and lower hypervigilance score (P < .04) were significantly associated with a better outcome. From 'during-treatment factors' a higher CBT 'proficiency score' ([a] acceptance of the explanation that SGB is a behavioural phenomenon [b] detection of a warning signal before belching [c] adherence to the exercises treatment) was associated with a better outcome (P = .001). Multiple regression analysis found that number of SGBs, hypervigilance score and CBT proficiency score were independently associated with outcome (P < .01, P = .01, P < .01). VAS score before CBT (267 ± 79) decreased to 151 ± 88 soon after CBT (P < .001), and the effect persisted at 6-12 months follow-up (153 ± 82).
Lower number of SGBs, lower hypervigilance score and higher proficiency during CBT were associated with better CBT outcome. CBT positive effect lasted for at least 6-12 months post-treatment.
胃上嗳气（SGB）具有显著的行为学成分。我们最近使用认知行为疗法（CBT）来治疗 SGB。我们发现，在完成治疗的患者中，有 50%的患者症状显著减轻，生活质量得到改善。
研究 CBT 治疗 SGB 成功的相关因素，并评估 CBT 治疗结束后 6-12 个月的症状。
分析了 39 例完成 CBT 方案的患者的记录。使用视觉模拟评分（VAS）评估治疗前后症状的百分比变化。我们评估了“治疗前”因素和“治疗中”因素与症状结果之间的关系。治疗结束后 6-12 个月还评估了症状。
从“治疗前因素”来看，嗳气次数较少（P<.01）和警觉评分较低（P<.04）与更好的结果显著相关。从“治疗中因素”来看，CBT“熟练程度评分”较高（a）接受嗳气是一种行为现象的解释，b）在嗳气前检测到预警信号，c）坚持治疗练习）与更好的结果相关（P=.001）。多元回归分析发现，嗳气次数、警觉评分和 CBT 熟练程度评分与结果独立相关（P<.01，P=.01，P<.01）。CBT 前 VAS 评分（267±79）在 CBT 后立即降至 151±88（P<.001），并且在 6-12 个月的随访中仍有效果（153±82）。
嗳气次数较少、警觉评分较低和 CBT 期间的熟练程度较高与 CBT 结果较好相关。CBT 的积极效果至少持续 6-12 个月。
