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普通民众使用不同类型止血带时美国外科医师学会出血控制基础培训的效果:一项随机临床试验。

Effectiveness of the American College of Surgeons Bleeding Control Basic Training Among Laypeople Applying Different Tourniquet Types: A Randomized Clinical Trial.

机构信息

Center for Surgery and Public Health, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

出版信息

JAMA Surg. 2019 Oct 1;154(10):923-929. doi: 10.1001/jamasurg.2019.2275.

Abstract

IMPORTANCE

More than 500 000 laypeople in the United States have been trained in hemorrhage control, including tourniquet application, under the Stop the Bleed campaign. However, it is unclear whether after hemorrhage control training participants become proficient in a specific type of tourniquet or can also use other tourniquets effectively.

OBJECTIVE

To assess whether participants completing the American College of Surgeons Bleeding Control Basic (B-Con) training with Combat Application Tourniquets (CATs) can effectively apply bleeding control principles using other tourniquet types (commercial and improvised).

DESIGN, SETTING, AND PARTICIPANTS: This nonblinded, crossover, sequential randomized clinical trial with internal control assessed a volunteer sample of laypeople who attended a B-Con course at Gillette Stadium and the Longwood Medical Area in Boston, Massachusetts, for correct application of each of 5 different tourniquet types immediately after B-Con training from April 4, 2018, to October 9, 2018. The order of application varied for each participant using randomly generated permutated blocks.

INTERVENTIONS

Full B-Con course, including cognitive and skill sessions, that taught bleeding care, wound pressure and packing, and CAT application.

MAIN OUTCOMES AND MEASURES

Correct tourniquet application (applied pressure of ≥250 mm Hg with a 2-minute time cap) in a simulated scenario for 3 commercial tourniquets (Special Operation Forces Tactical Tourniquet, Stretch-Wrap-and-Tuck Tourniquet, and Rapid Application Tourniquet System) and improvised tourniquet compared with correct CAT application as an internal control using 4 pairwise Bonferroni-corrected comparisons with the McNemar test.

RESULTS

A total of 102 participants (50 [49.0%] male; median [interquartile range] age, 37.5 [27.0-53.0] years) were included in the study. Participants correctly applied the CAT at a significantly higher rate (92.2%) than all other commercial tourniquet types (Special Operation Forces Tactical Tourniquet, 68.6%; Stretch-Wrap-and-Tuck Tourniquet, 11.8%; Rapid Application Tourniquet System, 11.8%) and the improvised tourniquet (32.4%) (P < .001 for each pairwise comparison). When comparing tourniquets applied correctly, all tourniquet types had higher estimated blood loss, had longer application time, and applied less pressure than the CAT.

CONCLUSIONS AND RELEVANCE

The B-Con principles for correct CAT application are not fully translatable to other commercial or improvised tourniquet types. This study demonstrates a disconnect between the B-Con course and tourniquet designs available for bystander first aid, potentially stemming from the lack of consensus guidelines. These results suggest that current B-Con trainees may not be prepared to care for bleeding patients as tourniquet design evolves.

TRIAL REGISTRATION

ClinicalTrials.gov identifier: NCT03538379.

摘要

重要性

在美国,已有超过 50 万名非专业人士接受了包括止血带应用在内的出血控制培训,这是“停止出血”运动的一部分。然而,目前尚不清楚在接受出血控制培训后,参与者是否能够熟练掌握特定类型的止血带,或者是否能够有效地使用其他类型的止血带。

目的

评估接受美国外科医师学院出血控制基础(B-Con)培训并使用战斗应用止血带(CATs)的参与者是否能够有效地使用其他类型的止血带(商业和临时)来应用出血控制原则。

设计、设置和参与者:本非盲、交叉、顺序随机临床试验采用内部对照方法,评估了参加了在马萨诸塞州波士顿吉尔利特体育场和朗伍德医疗区举行的 B-Con 课程的志愿者样本,这些志愿者是在 2018 年 4 月 4 日至 2018 年 10 月 9 日之间参加 B-Con 培训后,立即对 5 种不同类型的止血带(3 种商业止血带[特种作战部队战术止血带、拉伸包裹和系紧止血带、快速应用止血带系统]和临时止血带)的正确应用进行评估。每个参与者的应用顺序使用随机生成的排列块进行变化。

干预措施

完整的 B-Con 课程,包括认知和技能课程,教授出血护理、伤口压力和包扎以及 CAT 应用。

主要结果和测量指标

在模拟场景中对 3 种商业止血带(特种作战部队战术止血带、拉伸包裹和系紧止血带、快速应用止血带系统)和临时止血带的正确应用(应用压力≥250mmHg,时间限制为 2 分钟)与正确的 CAT 应用进行比较,CAT 应用作为内部对照。使用 4 个两两 Bonferroni 校正的 McNemar 检验进行比较。

结果

共有 102 名参与者(50 名[49.0%]男性;中位数[四分位距]年龄为 37.5[27.0-53.0]岁)纳入研究。参与者使用 CAT 的正确应用率(92.2%)显著高于所有其他商业止血带类型(特种作战部队战术止血带 68.6%、拉伸包裹和系紧止血带 11.8%、快速应用止血带系统 11.8%)和临时止血带(32.4%)(每项两两比较均 P<0.001)。当比较正确应用的止血带时,所有止血带类型的估计失血量更高,应用时间更长,应用压力均低于 CAT。

结论和相关性

B-Con 中正确应用 CAT 的原则并不能完全转化为其他商业或临时止血带类型。本研究表明,旁观者急救中可用的 B-Con 课程和止血带设计之间存在脱节,这可能源于缺乏共识指南。这些结果表明,随着止血带设计的不断发展,目前的 B-Con 培训人员可能无法准备好为出血患者提供护理。

试验注册

ClinicalTrials.gov 标识符:NCT03538379。

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