Carvalho Patrícia Paiva, Barroso Sabrina Martins, Coelho Heloisa Correa, Penaforte Fernanda Rodrigues de Oliveira
Hospital de Clínicas, Universidade Federal do Triângulo Mineiro (UFTM). Av. Getúlio Guaritá 130, Nossa Sra. da Abadia. 38025-440 Uberaba MG Brasil.
Departamento de Psicologia, UFTM. Uberaba MG Brasil.
Cien Saude Colet. 2019 Jul 22;24(7):2543-2555. doi: 10.1590/1413-81232018247.22312017.
AIDS is an advanced clinical manifestation of HIV infection. It generates severe immunodeficiency and associated infections that may lead to death. The antiretroviral therapy (ART) has reduced the morbimortality of HIV/AIDS, but its benefits depend on ART adherence. This integrative review followed the PICO method to identify factors associated with adult adherence to ART. Empirical papers published between January 2010 and December 2016 in the Medline, SciELO, Lilacs and PePSIC databases were included. We analyzed 125 papers regarding the characteristics of studies, adherence measures and associated factors. Results showed a wide variety in the definition of adherence and the use of measures for its monitoring, as well as several adherence-associated factors. These were categorized as follows: 1- Individual variables; 2- Treatment characteristics; 3- HIV/aids infection characteristics; 4- Relationship with the health services; 5- Social support. Health services should characterize the users' profiles, systematize adherence measures and regionally assess adherence-associated factors for the early detection of non-adherence to ART and implementation of effective intervention plans.
艾滋病是艾滋病毒感染的晚期临床表现。它会导致严重的免疫缺陷及相关感染，可能会导致死亡。抗逆转录病毒疗法（ART）降低了艾滋病毒/艾滋病的发病率和死亡率，但其疗效取决于对ART的依从性。本系统综述采用PICO方法，以确定与成人ART依从性相关的因素。纳入了2010年1月至2016年12月期间在Medline、SciELO、Lilacs和PePSIC数据库中发表的实证论文。我们分析了125篇关于研究特征、依从性测量方法及相关因素的论文。结果显示，依从性的定义及其监测方法存在很大差异，同时还有几个与依从性相关的因素。这些因素可分为以下几类：1-个体变量；2-治疗特征；3-艾滋病毒/艾滋病感染特征；4-与卫生服务的关系；5-社会支持。卫生服务机构应了解使用者的情况，系统化依从性测量方法，并对依从性相关因素进行区域评估，以便早期发现ART治疗不依从情况并实施有效的干预计划。
