Ruggiero Vickie J, Bartlett Paul C
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48823, USA.
Vet Med Int. 2019 Jun 25;2019:3202184. doi: 10.1155/2019/3202184. eCollection 2019.
The objective of this trial was to evaluate a test-and-cull approach to controlling bovine leukemia virus (BLV) in US dairy herds with a low BLV prevalence. Despite worldwide distribution of the virus, 21 nations have eradicated BLV from their dairy cattle and are currently considered 'BLV-free.' In contrast, the US has attempted no industry-wide BLV control programs and has experienced an increase in BLV prevalence among dairy cows to about 40%. This raises concerns about production efficiency, herd health, and sustainability. In a pilot field trial with three Midwestern-US dairy herds, a test-and-cull approach using ELISA screening of milk samples was successful in reducing BLV prevalence in two herds. In the third herd, BLV prevalence increased following the introduction of infected heifers that were raised at an out-of-state calf raising facility. This trial demonstrated that a test-and-cull approach to BLV control can be successful in US dairy herds with low BLV prevalence, but ongoing surveillance is necessary to prevent reintroduction of the virus.
本试验的目的是评估一种检测并淘汰的方法，用于控制美国低牛白血病病毒（BLV）流行率的奶牛群中的BLV。尽管该病毒在全球范围内传播，但已有21个国家从其奶牛群中根除了BLV，目前被认为“无BLV”。相比之下，美国尚未尝试实施全行业的BLV控制计划，且奶牛群中BLV的流行率已上升至约40%。这引发了对生产效率、畜群健康和可持续性的担忧。在美国中西部的三个奶牛群进行的一项田间试验中，使用ELISA对牛奶样本进行筛查的检测并淘汰方法成功降低了两个牛群中的BLV流行率。在第三个牛群中，引入在州外犊牛饲养场饲养的感染小母牛后，BLV流行率上升。该试验表明，对于美国BLV流行率较低的奶牛群，检测并淘汰的BLV控制方法可能会成功，但需要持续监测以防止病毒再次传入。
