Leite Milena Gomes Melo, Freitas Eliandro de Souza, de Vasconcelos Ii Antonio Jorge Araújo, Pinheiro Tiago Novaes
Undergraduate Student, Superior School of Health Science, Amazonas State University, Av. Carvalho Leal, 1777, Cachoeirinha, Manaus-AM, 69065-001, Brazil.
DDS, MSc, Superior School of Health Science, Amazonas State University, Av. Carvalho Leal, 1777, Cachoeirinha, Manaus-AM, 69065-001, Brazil.
J Lasers Med Sci. 2020 Summer;11(3):348-354. doi: 10.34172/jlms.2020.56. Epub 2020 Jun 21.
Necrotizing sialometaplasia (NS) is a rare locally destructive inflammatory benign disease that commonly affects the minor salivary glands. It is frequently associated with the glands located in the posterior portion of the hard and soft palates. Low-level laser therapy (LLLT), also called photobiomodulation therapy (PBMT), has been deemed a substantial method for the regenerative wound process. A 32-year-old male patient was referred with a chief complaint of two asymptomatic crater-like ulcers measuring approximately 1.5 cm wide on the right side of the hard and soft palates, and another measuring 0.3 cm wide on the left side of the hard palate. The lesion had two weeks of evolution followed by a previous infectious "sore throat" event that kept the patient hospitalized for 4 days. A clinical diagnosis of NS was made. LLLT was applied during 2 sessions per week, favoring the total wound healing within 2 weeks. At 3 months of clinical followup, the patient did not present any complication or relapse and was thus released. This is, to our knowledge, the first clinical report of LLLT applied for the management of NS. Large palatal ulcers caused by NS usually have long healing periods. The shortened healing period observed in this case encourages the inclusion of LLLT in any treatment protocol for similar lesions.
坏死性涎腺化生（NS）是一种罕见的具有局部破坏性的炎症性良性疾病，通常累及小涎腺。它常与位于硬腭和软腭后部的腺体相关。低强度激光治疗（LLLT），也称为光生物调节疗法（PBMT），已被认为是促进伤口再生过程的一种重要方法。一名32岁男性患者因主要症状就诊，其右侧硬腭和软腭有两个无症状的火山口样溃疡，直径约1.5厘米，左侧硬腭有一个直径0.3厘米的溃疡。该病变已发展两周，之前有一次感染性“喉咙痛”事件，患者因此住院4天。临床诊断为NS。每周进行2次LLLT治疗，促使伤口在2周内完全愈合。在临床随访3个月时，患者未出现任何并发症或复发，因此出院。据我们所知，这是LLLT用于治疗NS的首例临床报告。由NS引起的腭部大溃疡通常愈合期较长。本病例中观察到的愈合期缩短促使在任何类似病变的治疗方案中纳入LLLT。
