National Institute of Bioengineering (INABIO), Universidad Central de Venezuela, c/ Miguel Otero Silva s/n, Caracas, Venezuela.
Department of Materials Science and Metallurgy, Universitat Politècnica de Catalunya, Av. Eduard Maristany 10-14, 08019, Barcelona, Spain.
J Mater Sci Mater Med. 2019 Jul 25;30(8):90. doi: 10.1007/s10856-019-6291-1.
The aim of this study was to evaluate the biomechanical behavior of Bone Level dental implants with four different neck designs in contact with cortical bone. Numerical simulations were performed using a Finite Element Method (FEM) based-model. In order to verify the FEM model, the in silico results were compared with the results obtained from histological analysis performed in an in vivo study with New Zealand rabbits. FEM was performed using a computerized 3D model of Bone Level dental implants inserted in the lower jaw bone with an applied axial load of 100 N. The analysis was performed using four different implant neck designs: even surfaced, screwed, three-ring design and four-ring design. Interface are of bone growth was evaluated by analyzing the Bone-Implant-Contact (BIC) parameter obtained from in vivo histological process and analyzed by Scanning Electron Microscopy (SEM). Bone Level implants were inserted in the rabbit tibia, placing two implants per tibia. The BIC was evaluated after three and six weeks of implantation. FEM studies showed that the three-ring design presented lower values of stress distribution compared to the other studied designs. The lower levels of mechanical stress were then correlated with the in vivo studies, showing that the three-ring design presented the highest BIC value after 3 and 6 weeks of implantation. In silico and in vivo results both concluded that the implants with three-ring neck design presented the best biomechanical and histological behavior in terms of new bone formation, enhanced mechanical stability and optimum osseointegration.
本研究旨在评估四种不同颈部设计的骨水平种植体与皮质骨接触时的生物力学行为。使用基于有限元方法（FEM）的模型进行数值模拟。为了验证 FEM 模型，将计算机模拟结果与在新西兰兔体内研究中进行的组织学分析结果进行了比较。使用计算机化的下颌骨中插入的骨水平种植体的三维模型进行 FEM，施加 100N 的轴向载荷。分析使用了四种不同的种植体颈部设计：光滑表面、螺旋、三环设计和四环设计。通过分析从体内组织学过程中获得的骨-种植体接触（BIC）参数来评估骨生长界面，并用扫描电子显微镜（SEM）进行分析。将骨水平种植体插入兔胫骨中，每根胫骨放置两个种植体。在植入后 3 周和 6 周评估 BIC。FEM 研究表明，三环设计的应力分布值低于其他研究设计。然后，较低的机械应力水平与体内研究相关，表明三环设计在植入后 3 周和 6 周时具有最高的 BIC 值。计算机模拟和体内研究都得出结论，三环颈部设计的种植体在新骨形成、增强机械稳定性和最佳骨整合方面表现出最佳的生物力学和组织学行为。
