Schully Kevin L, Burtnick Mary N, Bell Matthew G, Spall Ammarah, Mayo Mark, Rigas Vanessa, Chan Alyssa A, Yu Kathleen, Clark Danielle V, Maves Ryan C, Currie Bart J, Brett Paul J, Lawler James V
MSMR. 2019 Jul;26(7):8-17.
Infection with the gram-negative bacterium can result in a life-threatening disease known as melioidosis. Historically, melioidosis was a common infection in military forces serving in Southeast Asia, and it has the potential to have a serious impact on force health readiness. With the U.S. Department of Defense's increasing strategic and operational focus across the Pacific Theater, melioidosis is an increasingly important issue from a force health protection perspective. U.S. Marines deploy annually to Darwin, Australia, a "hyperendemic" region for , to engage in training exercises. In an effort to assess the risk of infection to service personnel in Australia, 341 paired samples, representing pre- and post-deployment samples of Marines who trained in Australia, were analyzed for antibodies against antigens. Serological evidence of possible deployment-related infection with was found in 13 Marines. Future prospective studies are required to further characterize the risk to service members deployed to melioidosis endemic areas.
感染革兰氏阴性菌可导致一种名为类鼻疽的危及生命的疾病。从历史上看,类鼻疽在东南亚服役的军队中是一种常见感染,并且它有可能对部队健康准备状态产生严重影响。随着美国国防部在整个太平洋战区的战略和行动重点不断增加,从部队健康保护的角度来看,类鼻疽是一个日益重要的问题。美国海军陆战队每年部署到澳大利亚达尔文,这是一个类鼻疽“高度流行”地区,以参加训练演习。为了评估澳大利亚服务人员感染类鼻疽的风险,对341对样本进行了分析,这些样本代表了在澳大利亚训练的海军陆战队部署前和部署后的样本,以检测针对类鼻疽抗原的抗体。在13名海军陆战队队员中发现了可能与部署相关的类鼻疽感染的血清学证据。需要未来的前瞻性研究来进一步确定部署到类鼻疽流行地区的服务人员所面临的风险特征。