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对接受可变磁场治疗的特发性髋骨关节炎男性患者的β-内啡肽浓度、情绪和疼痛强度的评估。

Evaluation of β-endorphin concentration, mood, and pain intensity in men with idiopathic hip osteoarthritis treated with variable magnetic field.

作者信息

Koczy Bogdan, Stołtny Tomasz, Pasek Jarosław, Leksowska-Pawliczek Maria, Czech Szymon, Ostałowska Alina, Kasperczyk Sławomir, Białkowska Monika, Cieślar Grzegorz

机构信息

District Hospital of Orthopaedics and Trauma Surgery in Piekary Śląskie, Piekary Śląskie.

Institute of Physical Education, Tourism and Physiotherapy, Jan Długosz University in Częstochowa, Częstochowa.

出版信息

Medicine (Baltimore). 2019 Jul;98(30):e16431. doi: 10.1097/MD.0000000000016431.

DOI:10.1097/MD.0000000000016431
PMID:31348243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6708614/
Abstract

Osteoarthritis is the most frequently diagnosed disease of the musculoskeletal system. Growing number of patients waiting for surgical treatment and the possible negative consequences resulting from long-term pharmacological therapy lead to the search for non-pharmacological methods aimed at alleviating pain and reducing doses of analgesics, among them physical therapy with use of magnetic fields.The study involved 30 men aged 49 to 76 (mean age, 61.7 years) treated for idiopathic osteoarthritis of the hip joint. The subjects were divided into 2 groups (15 patients each) and underwent a cycle of magnetostimulation and magnetoledtherapy procedures, respectively. During the exposure cycle concentrations of β-endorphin were assessed 3 times and the mood was assessed 2 times. In addition, the assessment of pain intensity and the dose of analgesic drugs was performed before and after the end of therapy.Statistically significant increase in plasma β-endorphins concentration was observed in both groups of patients (magnetostimulation-P < .01 vs magnetoledtherapy-P < .001). In the assessment of mood of respondents, no statistically significant differences were found. Significant reduction in intensity of perceived pain was observed in both groups of patients (P < .05). In the group of patients who underwent magnetoledtherapy cycle, the analgesic drug use was significantly lower by 13% (P < .05) as compared with initial values, which was not noted in group of patients who underwent magnetostimulation procedures.The use of magnetic field therapy in the treatment of men with idiopathic osteoarthritis of hip joints causes a statistically significant increase in the concentration of plasma β-endorphins resulting in statistically significant analgesic effect in both magnetostimulation and magnetoledtherapy treated groups of patients, with accompanying decrease of need for analgetic drugs in magnetoledtherapy group, but without any significant changes regarding the patient's mood.

摘要

骨关节炎是肌肉骨骼系统中最常被诊断出的疾病。等待手术治疗的患者数量不断增加,以及长期药物治疗可能产生的负面后果,促使人们寻找旨在减轻疼痛和减少镇痛药剂量的非药物方法,其中包括使用磁场的物理治疗。该研究纳入了30名年龄在49至76岁(平均年龄61.7岁)的男性,他们因特发性髋关节骨关节炎接受治疗。受试者被分为两组(每组15名患者),分别接受了磁刺激和磁光疗法的治疗周期。在治疗周期中,β-内啡肽浓度被评估了3次,情绪被评估了2次。此外,在治疗结束前后对疼痛强度和镇痛药剂量进行了评估。两组患者的血浆β-内啡肽浓度均出现了统计学上的显著升高(磁刺激组P<0.01,磁光疗法组P<0.001)。在对受访者情绪的评估中,未发现统计学上的显著差异。两组患者的疼痛感知强度均出现了显著降低(P<0.05)。在接受磁光疗法治疗周期的患者组中,与初始值相比,镇痛药的使用量显著降低了

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/4b84e33c7e09/medi-98-e16431-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/6a6c04b8784b/medi-98-e16431-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/45146e072327/medi-98-e16431-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/9031f906e19a/medi-98-e16431-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/4b84e33c7e09/medi-98-e16431-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/6a6c04b8784b/medi-98-e16431-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/45146e072327/medi-98-e16431-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/9031f906e19a/medi-98-e16431-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f2/6708614/4b84e33c7e09/medi-98-e16431-g005.jpg

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