Department of Preventive Oncology, Tata Memorial Hospital, Mumbai, India.
Oral Dis. 2019 Oct;25(7):1724-1734. doi: 10.1111/odi.13166. Epub 2019 Aug 19.
Oral cavity cancers are fourth most common cancers among Indian women. The objectives were to create cancer awareness (CA) and screen tobacco-using women for oral cavity cancers.
A community-based CA and screening programme was conducted among women in Mumbai, India. The tobacco-using women participated in CA and oral cavity screening by oral visual inspection (OVI). All screen-positive women were referred to nodal hospital and assisted for diagnostic confirmation and treatment completion.
Twelve slum clusters comprising of 138,383 population and 13,492 tobacco-using women have been covered. Among them, 11,895 (88.2%) participated in CA and 11,768 (87.2%) in OVI. A total of 377 (3.2%) women were screened positive, 275 (72.9%) complied with referral and 207 oral precancers [173 leukoplakia, 9 erythroplakia, 3 erythroleukoplakia and 41 sub-mucus fibrosis (SMF) including 35 women with multiple precancers] and 7 oral cancers were diagnosed. The detection rate of oral precancerous lesions and oral cancers was 17.6 and 0.6 per 1,000 screened women. Thirty-five women had multiple oral precancerous lesions. The results of multivariate analysis indicate dose-response relationship between tobacco use and risk of oral precancers.
Good participation rates (>85%) for cancer awareness and OVI were seen among urban slum women in India. Many oral precancer and cancer cases were detected and were managed at the nodal hospital.
口腔癌是印度女性中第四大常见癌症。目的是提高对口腔癌的认识并对吸烟女性进行口腔癌筛查。
在印度孟买的社区中开展了一项基于社区的提高认识和筛查计划，让吸烟女性通过口腔目视检查（OVI）参与口腔癌的认识和筛查。所有筛查阳性的女性都被转介到淋巴结医院，协助进行诊断确认和治疗完成。
涵盖了 138383 名居民和 13492 名吸烟女性的 12 个贫民窟集群。其中，11895 名（88.2%）参与了提高认识活动，11768 名（87.2%）参与了 OVI。共有 377 名（3.2%）女性筛查阳性，275 名（72.9%）符合转诊要求，207 名患有口腔癌前病变[173 名白斑，9 名红斑，3 名红白斑和 41 名黏膜下纤维化（SMF），其中 35 名女性患有多种癌前病变]和 7 名口腔癌被诊断。口腔癌前病变和口腔癌的检出率分别为每 1000 名筛查女性 17.6 和 0.6。35 名女性患有多种口腔癌前病变。多变量分析的结果表明，吸烟与口腔癌前病变的风险之间存在剂量反应关系。
印度城市贫民窟女性对提高认识和 OVI 的参与率很高（>85%）。发现了许多口腔癌前病变和癌症病例，并在淋巴结医院得到了管理。
