Wadde Kavita Ramesh, Gajare Priyanka Prakash, Sachdev Sanpreet Singh, Singhavi Hitesh Rajendra
Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Mumbai, Maharashtra, India.
Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Mumbai, Maharashtra, India.
Ann Maxillofac Surg. 2024 Jan-Jun;14(1):76-80. doi: 10.4103/ams.ams_181_23. Epub 2024 Apr 15.
To determine the characteristics of oral erythroplakia (OE) on a global scale, it is important to analyse and evaluate findings from various studies conducted across multiple geographical locations.
This review was conducted to determine the prevalence and malignant transformation rate (MTR) of OE.
A systematic search was performed to identify studies reporting the prevalence and MTR of OE across various databases - PubMed, Web of Science, Google Scholar, Elsevier and ScienceDirect without any restriction for the time of publication.
This review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines, and the protocol was registered in the PROSPERO database (ID: CD42023395215).
The prevalence rate of OE reported across the studies ranged from 0.04% to 1.14% with a mean of 0.25 + 0.002%. The MTRs reported across the studies included ranged from 2.6% to 65% with a mean of 30 ± 0.2%.
Based on the findings from the present review, it can be concluded that while the range of MTRs of OE varies widely across different geographical locations, the average rate can be considered 30%. The review also identified a need for conducting more studies on the prevalence rates as well as longitudinal studies assessing the MTR across different regions.
为了在全球范围内确定口腔红斑（OE）的特征，分析和评估在多个地理位置进行的各种研究结果非常重要。
进行本次综述以确定OE的患病率和恶性转化率（MTR）。
进行了系统检索，以识别在各种数据库（PubMed、科学网、谷歌学术、爱思唯尔和科学Direct）中报告OE患病率和MTR的研究，对发表时间没有任何限制。
本综述遵循系统评价和Meta分析的首选报告项目（PRISMA）声明指南，该方案已在PROSPERO数据库中注册（ID：CD42023395215）。
各项研究报告的OE患病率在0.04%至1.14%之间，平均为0.25 + 0.002%。各项研究报告的MTR在2.6%至65%之间，平均为30 ± 0.2%。
基于本次综述的结果，可以得出结论，虽然OE的MTR范围在不同地理位置差异很大，但平均率可认为是30%。该综述还指出需要对患病率进行更多研究以及开展评估不同地区MTR的纵向研究。
