Alwashmi Meshari F, Mugford Gerald, Abu-Ashour Waseem, Nuccio Misa
Memorial University, St. John's, NL, Canada.
Blue Mesa Health, New York, NY, United States.
JMIR Diabetes. 2019 Jul 26;4(3):e13904. doi: 10.2196/13904.
The prevalence of diabetes is increasing among adults globally. Research has demonstrated that a diabetes prevention program (DPP), which focuses on developing and maintaining health-promoting lifestyle modifications, can prevent or delay the onset of type 2 diabetes among at-risk individuals. The implementation of a digitally adapted DPP has the potential to prevent prediabetes on a national and global scale by using technology and behavior change science.
This study aimed to investigate the effects of a novel digital therapeutic DPP (Transform) on weight loss, body mass index (BMI), exercise frequency, and work absenteeism.
This study was a secondary analysis of retrospective data of adults with prediabetes who were enrolled in the Transform DPP from December 2016 to December 2017. The program incorporates interactive mobile computing, remote monitoring, an evidence-based curriculum, behavior tracking tools, health coaching, and online peer support to prevent or delay the onset of type 2 diabetes. The analysis included data that were collected at baseline and after 4 months of the Transform DPP.
The sample (N=273) comprised people with prediabetes who completed 4 months of the Transform program. Participants included 70.3% women, with a mean age of 54.0 (SD 11.2) years. On average, participants decreased their weight by 13.3 lbs (6.5%) and their BMI by 1.9 kg/m. On average, participants increased their exercise frequency by 1.7 days per week, and absenteeism was reduced by almost half a day per month.
These results suggest that the digital therapeutic DPP (Transform) is effective at preventing type 2 diabetes through a significant reduction in body weight and an increase of physical activity. A prospective, controlled clinical study is warranted to validate these findings.
全球成年人中糖尿病的患病率正在上升。研究表明，一项专注于培养和维持促进健康的生活方式改变的糖尿病预防计划（DPP），可以预防或延缓高危个体患2型糖尿病。通过使用技术和行为改变科学，实施数字化适配的DPP有潜力在国家和全球范围内预防糖尿病前期。
本研究旨在调查一种新型数字治疗性DPP（Transform）对体重减轻、体重指数（BMI）、运动频率和旷工的影响。
本研究是对2016年12月至2017年12月参加Transform DPP的糖尿病前期成年人回顾性数据的二次分析。该计划结合了交互式移动计算、远程监测、循证课程、行为跟踪工具、健康指导和在线同伴支持，以预防或延缓2型糖尿病的发病。分析包括在Transform DPP基线和4个月后收集的数据。
样本（N = 273）包括完成4个月Transform计划的糖尿病前期患者。参与者中70.3%为女性，平均年龄为54.0（标准差11.2）岁。参与者平均体重减轻了13.3磅（6.5%），BMI降低了1.9 kg/m²。参与者平均每周运动频率增加1.7天，旷工每月减少近半天。
这些结果表明，数字治疗性DPP（Transform）通过显著减轻体重和增加身体活动，在预防2型糖尿病方面是有效的。有必要进行一项前瞻性对照临床研究来验证这些发现。
