Olayanju Jessica, Borras Teresa, Qaqish Bahjat, Fleischman David
Department of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina, USA.
North Carolina Translational and Clinical Sciences Institute, University of North Carolina, Chapel Hill, North Carolina, USA.
J Curr Glaucoma Pract. 2018 Sep-Dec;12(3):113-118. doi: 10.5005/jp-journals-10028-1255.
Determination of the effect of varying fenestration technique, and simulated patch graft on outflow facility for Baerveldt tube.
Silicone tubing similar to Baerveldt implant (AMO, Santa Ana, CA) with different fenestrations techniques was connected to a digital manometer in a closed system with a fluid-filled syringe on a stand to adjust pressure. The venting slits included: (A) 4 piercings with 7-0 TG140-8 needle; (B) a 2-mm slit with a 15° blade; (C) 4 piercings with a 15° blade; (D) 9-0 Nylon on CS140-6 needle with suture stenting the fenestration.
For pressures of 10, 20, 30, 40 mm Hg in groups A to D, the average outflow facility (mL/min/mm Hg) were group A: 0.11, 0.20, 0.28, 0.40; group B: 0.30, 0.69, 0.98, 0.93; group C: 0.73, 0.80, 0.81, 0.88; group D: 0.58, 0.65, 0.80, 0.87. For external compression with 10 gram weights at pressures of 10, 20, 30, 40 mm Hg, outflow were group A: 0.0, 0.18, 0.20, 0.53; group B: 0.75, 0.70, 0.97, 1.21. Group C: 0.18, 0.03, 0.57, 0.04. Group D: 0.73, 0.90, 1.13, 0.91.
Effectivity of venting slits in maintaining adequate IOP in the early postoperative period for non-valved glaucoma implant is variable, multifactorial and largely intraocular pressure (IOP) dependent.
This study explores methods of producing fenestration and the effects on outflow at different pressures in an attempt to determine which fenestration technique has more reproducible results that can be made applicable in clinical practice. This is also the first study to evaluate the effect of external pressures similar to scleral patch graft on the tube fenestrations.
Olayanju J, Borras T, Qaqish B, Fleischman D. Outflow Facility in Tube Shunt Fenestration. J Curr Glaucoma Pract 2018;12(3):113-118.
确定不同开窗技术及模拟补片移植对Baerveldt引流管房水流出度的影响。
将与Baerveldt植入物（AMO，加利福尼亚州圣安娜）类似的硅胶管采用不同开窗技术连接到一个封闭系统中的数字压力计上，该系统带有一个置于支架上的充满液体的注射器以调节压力。排气孔包括：（A）用7-0 TG140-8针穿刺4处；（B）用15°刀片切开一个2毫米的切口；（C）用15°刀片穿刺4处；（D）用CS140-6针穿9-0尼龙线并缝合支撑开窗处。
在A至D组中，压力为10、20、30、40毫米汞柱时，平均房水流出度（毫升/分钟/毫米汞柱）分别为：A组：0.11、0.20、0.28、0.40；B组：0.30、0.69、0.98、0.93；C组：0.73、0.80、0.81、0.88；D组：0.58、0.65、0.80、0.87。在压力为10、20、30、40毫米汞柱时用10克砝码进行外部压迫，房水流出量分别为：A组：0.0、0.18、0.20、0.53；B组：0.75、0.70、0.97、1.21；C组：0.18、0.03、0.57、0.04；D组：0.73、0.90、1.13、0.91。
对于无瓣膜的青光眼植入物，排气孔在术后早期维持足够眼压方面的有效性是可变的、多因素的，且很大程度上取决于眼压（IOP）。
本研究探索了开窗制作方法及其在不同压力下对房水流出的影响，试图确定哪种开窗技术能产生更可重复的结果并应用于临床实践。这也是第一项评估类似于巩膜补片移植的外部压力对引流管开窗影响的研究。
Olayanju J, Borras T, Qaqish B, Fleischman D. 引流管分流开窗的房水流出度。《当代青光眼实践杂志》2018；12(3):113 - 118。
